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7 postsExposure to hexavalent chromium and 1800 MHz electromagnetic radiation can synergistically induce intracellular DNA damage in mouse embryonic fibroblasts
This PubMed-listed in vitro study tested whether 1800 MHz RF-EMF exposure can modify chemically induced DNA damage in mouse embryonic fibroblasts under standardized, non-thermal conditions. The authors report RF-EMF alone did not produce detectable DNA damage and did not significantly increase damage from hydrogen peroxide, 4-nitroquinoline-1-oxide, or cadmium. However, co-exposure with hexavalent chromium (Cr(VI)) was reported to synergistically increase DNA damage in the comet assay, which the authors interpret as possible selective exacerbation of Cr(VI)-induced genotoxicity requiring further investigation.
Exposure to hexavalent chromium and 1800 MHz electromagnetic radiation can synergistically induce intracellular DNA damage in mouse embryonic fibroblasts
This in vitro study tested whether 1800 MHz RF-EMF modifies chemically induced DNA damage in mouse embryonic fibroblasts under non-thermal exposure conditions. RF-EMF alone did not produce detectable DNA damage and did not significantly enhance damage from hydrogen peroxide, 4NQO, or cadmium. In contrast, co-exposure with hexavalent chromium (Cr(VI)) was reported to synergistically increase DNA damage, suggesting a selective co-genotoxic interaction under specific chemical conditions.
Parametric analysis of electromagnetic wave interactions with layered biological tissues for varying frequency, polarization, and fat thickness
This PubMed-listed study models how RF electromagnetic waves interact with a simplified three-layer tissue structure (skin–fat–muscle) across common ISM bands (433, 915, 2450, 5800 MHz), varying polarization (TE/TM), incidence angle, and fat thickness. Using a custom MATLAB pipeline combining multilayer transmission-line methods, Cole–Cole dielectric parameters, and a steady-state Pennes bioheat solution, the authors estimate reflection, absorption, and resulting temperature rise. The simulations report small temperature increases at lower frequencies (433–915 MHz) and larger superficial heating at 5.8 GHz under the modeled conditions, highlighting how fat thickness and wave parameters modulate dosimetry and thermal outcomes.
Assessment of Electromagnetic Exposure to a Child and a Pregnant Woman Inside an Elevator in Mobile Frequencies
This study uses anatomically detailed computational models of a five-year-old girl, a pregnant woman in the third trimester, and a fetus to simulate mobile phone RF exposure inside an elevator cabin. Simulations at 1000 MHz and 1800 MHz across 48 configurations evaluated SAR10g, whole-body SAR, and maximum temperature. The abstract reports that configuration (positioning and phone orientation) can substantially change absorption and temperature metrics and calls for broader scenario testing to inform safety guidance for vulnerable populations.
An 1800 MHz Electromagnetic Field Affects Hormone Levels, Sperm Quality, and Behavior in Laboratory Rats
This animal study exposed rats to a 1800 MHz electromagnetic field for 12 weeks and assessed hormones, sperm quality, and behavior. The abstract reports increased corticosterone, decreased thyroid-stimulating hormone, reduced sperm motility/viability, and increased anxiety-like behavior in exposed rats. Some hormonal changes reportedly persisted for at least 2 weeks after exposure ended, and the authors frame the results as indicating adverse endocrine, reproductive, and behavioral effects.
Role of radio-frequency electromagnetic waves in causing oxidative stress
This animal study exposed fertilized chick eggs to a nearby 1800 MHz mobile phone that was called repeatedly (50 minutes/day) and assessed embryos at days 10 and 15. The exposed group reportedly showed mitochondrial abnormalities in liver, brain, and heart tissues on electron microscopy, along with increased HSP70 in cardiomyocytes and hepatocytes. The authors conclude that radio-frequency electromagnetic waves can induce oxidative stress and mitochondrial damage in developing embryos.
Effects of GSM modulated radio-frequency electromagnetic radiation on permeability of blood-brain barrier in male & female rats
This rat study examined whether pulse-modulated 900 MHz and 1800 MHz RF exposure affects blood-brain barrier permeability using Evans blue dye. The abstract reports increased permeability in male rats at both frequencies (stronger at 1800 MHz) and in female rats at 900 MHz but not at 1800 MHz. The authors suggest mobile-phone-like RF exposure could increase blood-brain barrier permeability under non-thermal conditions, while noting that further mechanistic studies are needed.