Cytotoxicity of temozolomide on human glioblastoma cells is enhanced by the concomitant exposure to an extremely low-frequency electromagnetic field (100Hz, 100G).
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study tested whether an extremely low-frequency EMF (100 Hz, 100 G) could enhance temozolomide cytotoxicity in human glioma cell lines (U87 and T98G). The authors report that combined EMF and temozolomide increased apoptosis relative to either treatment alone and was accompanied by changes in…
Extremely low frequency electromagnetic field (ELF-EMF) reduces oxidative stress and improves functional and psychological status in ischemic stroke patients.
Research
RF Safe Research Library
Jan 1, 2017
This clinical study evaluated whether adding ELF-EMF exposure to a 4-week rehabilitation program affects antioxidant and clinical status in ischemic stroke patients. Fifty-seven patients were assigned to an ELF-EMF group or a non-ELF-EMF group, with the exposed group receiving 40 Hz, 7 mT for 15 minutes per day over…
The influence of prenatal 10 GHz microwave radiation exposure on a developing mice brain.
Research
RF Safe Research Library
Jan 1, 2017
This animal study examined prenatal exposure to 10 GHz microwave radiation starting at gestation day 0.25 or 11.25 until term. At 3 weeks of age, offspring from exposed pregnancies showed reduced brain and body weight and biochemical changes consistent with oxidative stress compared with sham controls. The authors…
Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats.
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RF Safe Research Library
Jan 1, 2017
This animal study examined whole-body exposure to 2.45 GHz microwave radiation for 2 h/day over 35 days in male Wistar rats. The authors report increased lipid peroxidation (LPO) in liver, brain, and spleen and histological changes across multiple organs compared with sham-exposed controls. They conclude the exposure…
[Protective effects of Genistein on human renal tubular epithelial cells damage of microwave radiation].
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed human proximal renal tubular epithelial cells (HKC) to microwave irradiation for 24 hours and assessed cell injury, oxidative stress, and cell death. The authors report increased injury markers (LDH, NAG), increased oxidative stress (higher MDA, lower SOD), and more apoptosis/necrosis…
Electromagnetic Fields Act Similarly in Plants as in Animals: Probable Activation of Calcium Channels via Their Voltage Sensor
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RF Safe Research Library
Jan 1, 2016
This narrative review proposes that low-intensity microwave/lower-frequency EMFs activate plasma membrane calcium channels in animals, increasing intracellular calcium and triggering downstream signaling including oxidative stress pathways. It further suggests that EMF actions in terrestrial multicellular plants are…
Unraveling the effects of static magnetic field stress on cytosolic proteins of Salmonella by using a proteomic approach.
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study examined how Salmonella enterica serovar Hadar adapts to a 200 mT static magnetic field for 9 hours using proteomics. The authors report 35 cytosolic proteins with >2-fold expression changes after exposure, spanning metabolism, oxidative stress response, energy homeostasis, translation elongation,…
2.45 GHz Microwave Radiation Impairs Learning and Spatial Memory via Oxidative/Nitrosative Stress Induced p53-Dependent/Independent Hippocampal Apoptosis: Molecular Basis and Underlying Mechanism
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RF Safe Research Library
Jan 1, 2015
This animal study exposed male Swiss mice to 2.45 GHz continuous-wave microwave radiation for 2 hours/day over 15, 30, or 60 days. The authors report increased hippocampal oxidative/nitrosative stress and increased apoptosis in neuronal and nonneuronal hippocampal subfields. They also report duration-dependent…
A cross-sectional study on oxidative stress in workers exposed to extremely low frequency electromagnetic fields
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RF Safe Research Library
Jan 1, 2015
This cross-sectional study compared oxidative stress and genotoxicity biomarkers between 310 ELF-EMF-exposed inspection workers and 300 logistical staff controls. The authors report no statistically significant differences in antioxidant-related measures (T-AOC, GPx, SOD) or MDA, and no significant differences in…
Impacts of exposure to 900 MHz mobile phone radiation on liver function in rats.
Research
RF Safe Research Library
Jan 1, 2015
This animal experiment randomized 20 male Sprague-Dawley rats to 900 MHz electromagnetic radiation exposure (4 h/day for 18 days) or no exposure. The exposed group showed increased oxidative stress markers in liver tissue (higher MDA, lower GSH) and reported histopathological changes, along with increased apoptosis…
Data supporting the role of electric field and electrode material on the improvement of the ageing effects in hydrogenated amorphous silicon solar cells.
Research
RF Safe Research Library
Jan 1, 2015
This Data in Brief article provides additional experimental data supporting a related study on mitigating ageing effects (Staebler-Wronski effect) in hydrogenated amorphous silicon solar cells. The associated method involves applying reverse bias stress and evaluating how temperature, electric field intensity,…
[The combined action of drinking mineral water and low-intensity electromagnetic radiation under the immobilization stress conditions (an experimental study)].
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RF Safe Research Library
Jan 1, 2015
This animal experimental study examined combined exposure to potable mineral water and low-intensity ultrahigh-frequency electromagnetic radiation (~1000 MHz;
The Impact of Using Cell Phones After Light-Out on Sleep Quality, Headache, Tiredness, and Distractibility Among Students of a University in North of Iran.
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RF Safe Research Library
Jan 1, 2015
This cross-sectional study surveyed 358 university students about cell phone use after lights-out and related symptoms. Sixty percent reported late-night phone use, which was associated with insomnia, and initially with low energy, tiredness, and headache. After controlling for stressful events, only the association…
Strain in YBCO Double-Pancake Coil With Stainless Steel Overband Under External Magnetic Field.
Research
RF Safe Research Library
Jan 1, 2015
This engineering study evaluates mechanical hoop strain in a YBCO coated-conductor double-pancake coil intended for a high-field HTS insert in an NMR magnet. The authors present experimental strain-gauge measurements and analytical stress/strain calculations for a coil operated with and without a stainless steel…
Effects of extremely low frequency electromagnetic fields on paraoxonase serum activity and lipid peroxidation metabolites in rat
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RF Safe Research Library
Aug 13, 2014
This randomized animal experiment examined whether 60 Hz extremely low frequency magnetic field (ELF-MF) exposure alters oxidative stress-related biomarkers in 75 Wistar rats. The authors report increased lipid peroxidation markers after both single and 14-day exposures, alongside changes in antioxidant-related…
2.45-GHz microwave irradiation adversely affects reproductive function in male mouse, Mus musculus by inducing oxidative and nitrosative stress
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RF Safe Research Library
Jan 1, 2014
This animal study exposed 12-week-old male Swiss strain mice to non-thermal low-level 2.45-GHz microwave radiation for 2 hours per day over 30 days (SAR 0.018 W/kg). The abstract reports reduced sperm count and viability, testicular structural changes, lower 3β-HSD activity and plasma testosterone, and increased…
Electromagnetic radiation (Wi-Fi) and epilepsy induce calcium entry and apoptosis through activation of TRPV1 channel in hippocampus and dorsal root ganglion of rats
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RF Safe Research Library
Jan 1, 2014
This animal study examined 2.45 GHz Wi-Fi exposure in a PTZ-induced epilepsy rat model using freshly isolated hippocampal and DRG neurons. The authors report that epilepsy increased Ca(2+) influx, oxidative stress markers, and apoptosis-related outcomes, and that Wi-Fi exposure produced additional increases in…
Assessment of the neurotoxic potential of exposure to 50Hz extremely low frequency electromagnetic fields (ELF-EMF) in naïve and chemically stressed PC12 cells
Research
RF Safe Research Library
Jan 1, 2014
This in vitro study tested acute (30 min) and sub-chronic (48 h) 50 Hz ELF-EMF exposure up to 1000 µT in naïve and chemically stressed PC12 cells. Across assays of Ca2+ homeostasis, ROS production, and membrane integrity, the study reports no consistent or measurable neurotoxic effects under the tested conditions.…
Effect of 950 MHz UHF electromagnetic radiation on biomarkers of oxidative damage, metabolism of UFA and antioxidants in the livers of young rats of different ages
Research
RF Safe Research Library
Jan 1, 2014
This animal study exposed rats of different early-life ages to 950 MHz UHF electromagnetic radiation for 30 minutes per day (SAR 1.0–1.3 W/kg) across gestation and/or early postnatal periods. The authors report no evidence of oxidative stress by TBARS or protein carbonyls, but report changes in fatty acid…
[The activity of prooxidant-antioxidant system in loach embryos under the action of microwave radiation].
Research
RF Safe Research Library
Jan 1, 2014
This animal study examined oxidative stress and antioxidant defenses in loach embryos exposed to GSM 900 MHz microwave radiation (SAR 1.1 W/kg) for 1–20 minutes during early embryogenesis. The authors report significant changes in lipid peroxidation products and altered antioxidant enzyme activities. They conclude…
Modification of catalase and MAPK in Vicia faba cultivated in soil with high natural radioactivity and treated with a static magnetic field.
Research
RF Safe Research Library
Jan 1, 2014
This plant study examined effects of a 30 mT static magnetic field and cultivation in soil with high natural radioactivity on oxidative stress-related markers in Vicia faba. The abstract reports significant changes in catalase and MAPK gene expression in treated plants versus controls. Catalase activity and H2O2…
Spatial learning, monoamines and oxidative stress in rats exposed to 900 MHz electromagnetic field in combination with iron overload.
Research
RF Safe Research Library
Jan 1, 2014
This animal study tested whether 900 MHz EMF exposure, alone or combined with brain iron overload, affects cognition and brain biochemistry in Long-Evans rats. EMF-exposed rats showed impairment in an object exploration task and changes in monoamine content (notably in the hippocampus), while other spatial…
Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects
Research
RF Safe Research Library
Jan 1, 2013
This narrative review argues that non-thermal biological effects of extremely low and microwave frequency EMFs may be mediated by activation of voltage-gated calcium channels (VGCCs). It cites 23 studies in which VGCC blockers reportedly block or reduce diverse EMF effects and proposes downstream…
Microwave radiation induced oxidative stress, cognitive impairment and inflammation in brain of Fischer rats.
Research
RF Safe Research Library
Jan 1, 2012
This animal study exposed male Fischer-344 rats to 900 MHz or 1800 MHz microwave radiation for 30 days (2 h/day) and compared outcomes to sham exposure. The authors report significant cognitive impairment along with increased oxidative stress in brain tissue in exposed rats. They also report increased inflammatory…
Nanosecond pulse electric field activation of platelet-rich plasma reduces myocardial infarct size and improves left ventricular mechanical function in the rabbit heart.
Research
RF Safe Research Library
Jan 1, 2012
This animal and in vitro study evaluated nanosecond pulsed electric fields (nsPEF) as a nonchemical method to activate platelet-rich plasma (PRP) for cardioprotection. In rabbits undergoing brief coronary occlusion followed by reperfusion, PRP injection into ischemic myocardium was associated with reduced infarct…