Effect of exposure to extremely low frequency magnetic fields on melatonin levels in calves is seasonally dependent
Research
RF Safe Research Library
Sep 18, 2015
This animal study measured salivary melatonin in 1–2 month old calves exposed to 50 Hz extremely low frequency magnetic fields in the hundreds of nT range. The authors report a season-dependent response: melatonin decreased with exposure in winter but increased in summer. They suggest future studies should consider…
Effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure on B6C3F1 mice
Research
RF Safe Research Library
May 5, 2015
This long-term animal study exposed mice to a 50 Hz magnetic field (500 mG) prenatally and then through 15.5 months of life to assess tumor-related outcomes and fertility-related measures. Exposed mice had lower body weights and showed no increase in liver or lung tumor incidence. However, exposed female mice had a…
Experimental model for ELF-EMF exposure: Concern for human health.
Research
RF Safe Research Library
Jan 1, 2015
This in vitro study examined whether extremely low frequency EMF exposure alters MCP-1 expression in several human cell lines. Cells were exposed to a 50 Hz sinusoidal field at 1 mT (rms), and the authors report that MCP-1 expression was modified in a cell-type-dependent manner. The findings are described as…
Assessment of the neurotoxic potential of exposure to 50Hz extremely low frequency electromagnetic fields (ELF-EMF) in naïve and chemically stressed PC12 cells
Research
RF Safe Research Library
Jan 1, 2014
This in vitro study tested acute (30 min) and sub-chronic (48 h) 50 Hz ELF-EMF exposure up to 1000 µT in naïve and chemically stressed PC12 cells. Across assays of Ca2+ homeostasis, ROS production, and membrane integrity, the study reports no consistent or measurable neurotoxic effects under the tested conditions.…
No effects of power line frequency extremely low frequency electromagnetic field exposure on selected neurobehavior tests of workers inspecting transformers and distribution line stations versus controls
Research
RF Safe Research Library
Jan 1, 2014
This study evaluated whether occupational 50 Hz ELF-EMF exposure near transformers and distribution power lines affects performance on several computer-based neurobehavior tests. Spot measurements found some electric-field locations above a national occupational standard, while all magnetic-field spots were below the…
Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway.
Research
RF Safe Research Library
Jan 1, 2014
This in vitro study examined 50 Hz ELF-EMF effects on human T-type calcium channels expressed in HEK293 cells and on native T-type channels in primary cultured mouse cortical neurons. The authors report that ELF-EMF (0.2 mT) inhibited Cav3.1, Cav3.2, and Cav3.3 channel activity without changing Cav3.2 expression or…
P-selectin expression in a colon tumor model exposed by sinusoidal electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2013
This animal study evaluated whether sinusoidal magnetic field exposure alters P-selectin expression in a rat colon tumor model. Rats exposed to 50 Hz, 5 mT for 6 h/day for 8 months showed no statistically significant change in P-selectin expression by immunohistochemistry. The authors indicate that further in vitro…
Low-frequency electromagnetic fields do not alter responses of inflammatory genes and proteins in human monocytes and immune cell lines.
Research
RF Safe Research Library
Jan 1, 2012
This in vitro study examined whether low-frequency electromagnetic fields (a complex multiple waveform field and a 50 Hz sine wave) alter inflammatory gene and protein responses in human immune cells. Across time course experiments in THP-1 cells and primary monocytes/macrophages, the authors report no significant…
[Time effect of sinusoidal electromagnetic field on enhancing the maturation and mineralization of osteoblasts in vitro].
Research
RF Safe Research Library
Jan 1, 2011
This in vitro study exposed newborn rat calvarial osteoblasts to 50 Hz sinusoidal electromagnetic fields at 1.8 mT for different daily exposure times (0.5–3.0 h). The authors report inhibited osteoblast proliferation at longer exposure times, alongside increased differentiation markers (ALP activity) and…
Exposure to an additional alternating magnetic field affects comb building by worker hornets.
Research
RF Safe Research Library
Jan 1, 2007
This animal study reports that exposing worker oriental hornets in an artificial breeding box to an additional 50 Hz magnetic field (50–70 mGauss) altered comb construction compared with controls under only the terrestrial magnetic field. The abstract describes fewer cells and eggs, more deformed cell geometry, and…