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114 posts

Impact of Radiofrequency Electromagnetic Fields on Cardiac Activity at Rest: A Systematic Review of Healthy Human Studies

Research RF Safe Research Library Jan 1, 2025

This systematic review evaluated evidence on RF-EMF exposure and cardiac activity (heart rate and heart rate variability) in healthy humans at rest. Across 28 studies spanning 100 to 110,000 MHz and exposures from minutes to a week, most studies reported no significant effects on resting heart rate, and HRV findings were largely null under calm conditions. Some position-dependent HRV changes were reported, and the authors note possible effects during physiological challenges, but conclude evidence is insufficient for firm conclusions beyond resting healthy populations.

The modeling of the interaction of pulsed 5G/6G signals and the fine structure of human skin

Research RF Safe Research Library Jan 1, 2025

This paper uses advanced electromagnetic simulations of human skin microstructure to model exposure to realistic pulsed 5G/6G signals at 3.5, 27, 77, and 300 GHz. It reports localized, inhomogeneous absorption patterns linked to sweat glands and blood vessels, suggesting that treating skin as homogeneous may miss hotspots. The authors conclude that SAR-based standards may be inadequate for mmWave/sub-THz exposures and could underestimate potential risks, including possible nerve excitation.

Smartphone Usage Patterns and Sleep Behavior in Demographic Groups: Retrospective Observational Study

Research RF Safe Research Library Jan 1, 2025

This retrospective observational study analyzed Murmuras app data from 1074 participants in 2022 to examine demographic differences in smartphone use and nocturnal smartphone inactivity duration (a proxy for sleep-related behavior). Nighttime smartphone use increased, especially for social media and entertainment, and usage patterns varied by gender, age, education, and employment status. Most demographic groups showed no significant correlation between usage duration and nocturnal inactivity, although some subgroups showed correlations in either direction. The authors frame excessive nighttime smartphone use as potentially adverse for sleep and link this behavioral exposure to electromagnetic fields with sleep health risks.

Temporal change of outdoor RF-EMF levels in four European countries: a microenvironmental measurement study

Research RF Safe Research Library Jan 1, 2025

This microenvironmental measurement study assessed temporal trends in outdoor RF-EMF exposure between 2016 and 2023 in the Netherlands, Switzerland, Belgium, and Spain using harmonized walking-route measurements with exposimeters. The authors report no significant change in mobile base station (downlink) exposure between 2016 and 2023 and no consistent trend across microenvironments or countries. Reported median downlink exposure values ranged from 0.11 mW/m² (Switzerland, 2023) to 0.62 mW/m² (Netherlands, 2018).

Assessment of Electromagnetic Exposure to a Child and a Pregnant Woman Inside an Elevator in Mobile Frequencies

Research RF Safe Research Library Jan 1, 2025

This study uses anatomically detailed computational models of a five-year-old girl, a pregnant woman in the third trimester, and a fetus to simulate mobile phone RF exposure inside an elevator cabin. Simulations at 1000 MHz and 1800 MHz across 48 configurations evaluated SAR10g, whole-body SAR, and maximum temperature. The abstract reports that configuration (positioning and phone orientation) can substantially change absorption and temperature metrics and calls for broader scenario testing to inform safety guidance for vulnerable populations.

Effect of the radiation emitted from a cell phone on T lymphocytes in mice

Research RF Safe Research Library Jan 1, 2025

This mouse study examined whether cell phone radiation affects T lymphocytes over 2–8 weeks of exposure. CD4 and CD8 subset percentages were similar across groups, but after more than six weeks, exposed groups showed increased T-cell apoptosis and reduced transformation rates compared with shams. The study also reports decreased IL-10 and increased IL-12 in exposed groups, suggesting time-dependent immunological changes under the tested conditions.

Low frequency magnetic field exposure and neurodegenerative disease: systematic review of animal studies

Research RF Safe Research Library Jan 1, 2025

This systematic review synthesizes animal studies on low frequency magnetic field exposure in relation to neurodegenerative diseases. It reports no support for a causal induction of Alzheimer’s-type neuropathology in naive animals, while noting that evidence is too limited to draw strong conclusions for motor neuron disease, multiple sclerosis, and Parkinson’s disease regarding induced neuropathology. In models with pre-existing neurodegenerative disease, the review describes possible therapeutic effects on behavioral and neuroanatomical outcomes for dementia-related conditions, and no apparent effect on motor neuron disease progression.

Perspectives on terahertz honeybee sensing

Research RF Safe Research Library Jan 1, 2025

This paper describes measurements and simulations to support terahertz (THz) sensing of European honey bees for environmental monitoring. It reports dielectric characterization of bee body parts across 1–500 GHz, scattering-based validation of 3D-printed bee mockups, and THz imaging demonstrating detailed anatomical visualization. The work includes dosimetric simulations at 300 GHz to evaluate feasibility of non-invasive, continuous monitoring and notes potential relevance to assessing high-frequency EMF impacts on insect health and habitat safety.

Greater prevalence of symptoms associated with higher exposures to mobile phone base stations in a hilly, densely populated city in Mizoram, India

Research RF Safe Research Library Jan 1, 2025

This cross-sectional study compared 183 higher-exposed residents with 126 matched reference residents and assessed symptoms via questionnaire alongside in-home RF-EMF power density measurements from mobile phone base stations. Higher exposure (including proximity within 50 m and power densities of 5–8 mW/m2) was reported to be associated with increased symptom prevalence across mood-energy, cognitive-sensory, inflammatory, and anatomical categories. The authors conclude that current public exposure limits may be inadequate for long-term, non-thermal biological impacts and call for precautionary policy updates.

Does Electromagnetic Pollution in the ART Laboratory Affect Sperm Quality? A Cross-Sectional Observational Study.

Research RF Safe Research Library Jan 1, 2025

This cross-sectional observational study assessed sperm motility after one hour of in vitro exposure of semen samples to EMFs from different laboratory sources in an IVF setting. It reports a statistically significant reduction in progressive sperm motility after exposure to mobile phones and Wi-Fi repeaters, while other EMF-emitting equipment showed no significant effect. The authors interpret the findings as indicating a potential negative impact of specific RF sources and call for further research, alongside practical mitigation suggestions in IVF laboratories.

Effect of elevation on cumulative radiofrequency exposure from multiple communication towers

Research RF Safe Research Library Jan 1, 2025

This exposure assessment measured RF power density across different floors of a high-rise university building using a spectrum analyser and log-periodic antenna. Power density decreased from the ground to the third floor but peaked on the fourth (top) floor. The 900 MHz band showed the highest reported power density (1.16E-03 W/m2), and the authors suggest higher-floor occupants may experience higher RF exposure from nearby communication towers.

In-Situ Measurements of Radiofrequency Electromagnetic Fields Measurements Around 5G Macro Base Stations in the UK

Research RF Safe Research Library Jan 1, 2025

This exposure assessment performed RF spot measurements in line-of-sight to 56 active 5G macro base stations across 30 publicly accessible UK locations. Power density was measured across 420 MHz–6 GHz under multiple scenarios (background, streaming, downlink speed test, and extrapolated SS-RSRP decoding). Reported total RF and 5G-specific levels were within 1998 ICNIRP public reference levels, with 4G downlink contributing most of the measured exposure.

Exposure to 26.5 GHz, 5G modulated and unmodulated signal, does not affect key cellular endpoints of human neuroblastoma cells

Research RF Safe Research Library Jan 1, 2025

This in vitro study examined whether 26.5 GHz millimeter-wave exposure (continuous wave and 5G-modulated) affects key cellular endpoints in human neuroblastoma cells. Cells were exposed for 3 hours at SAR 1.25 W/kg using a reverberation-chamber system, with assessments including cell cycle and DNA damage. The study reports no effects from exposure alone or when combined with the oxidant menadione, while noting that additional studies across varied conditions are needed.

Mitigation of 3.5 GHz Electromagnetic Field-Induced BV2 Microglial Cytotoxicity by Polydeoxyribonucleotide

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed BV2 mouse microglial cells to 3.5 GHz EMF for 2 hours and reports reduced cell growth and increased apoptosis alongside oxidative stress and signaling changes. The authors report that ROS generation and activation of JNK-1/2 and p38 MAPK were key events in the observed cytotoxicity. Polydeoxyribonucleotide (PDRN) reportedly reduced several EMF-associated cytotoxicity markers, suggesting a potential mitigating effect under the tested conditions.

The influence of Wi-Fi on the mesonephros in the 9-day-old chicken embryo

Research RF Safe Research Library Jan 1, 2025

This animal study examined continual 2.4 GHz Wi‑Fi exposure (200–500 μW/m²) during 9 days of chicken embryo incubation and assessed the mesonephros at day 9. The authors report no adverse effects on general mesonephros development, but describe moderate degenerative changes and vascular congestion without inflammatory infiltrate. They also report significantly increased apoptotic and proliferating cells and up-regulation of caspase‑1 gene expression, interpreted as disruption of regulatory processes during development.

The proliferation rates of HT-1080 human fibrosarcoma cells can be accelerated or inhibited by weak static and extremely low frequency magnetic fields

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed HT-1080 human fibrosarcoma cells for 4 days to weak extremely low frequency magnetic fields (10 μT, 12–33 Hz) superimposed on a 45 μT static field. The authors report frequency- and amplitude-dependent increases or decreases in cell growth, including sharp inversions near 16.5 Hz with small parameter changes or reversal of the static field direction. Associated changes in membrane potential, intracellular calcium, and mitochondrial superoxide are presented as supporting a bioenergetic mechanism.

Bus-exposure matrix, a tool to assess bus drivers' exposure to physicochemical hazards

Research RF Safe Research Library Jan 1, 2025

This paper describes the development of a Bus-Exposure Matrix (BEM) to retrospectively estimate Swiss bus drivers’ exposures to 10 physicochemical hazards, including electric and magnetic fields. Measurements in representative buses were combined with technical inventories and INLA modeling to estimate annual exposures from 1985–2022. Reported trends include increasing peak noise and electric-field exposures over time, alongside decreases in several air pollution, vibration, and noise metrics.

A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses biological mechanisms and reported health effects of anthropogenic extremely low frequency (ELF) and wireless communication (WC) electromagnetic fields. It highlights oxidative stress and DNA damage as key mechanistic endpoints and proposes an IFO-VGIC pathway linking EMF exposure to ROS overproduction and cellular dysfunction. The authors interpret the broader literature as indicating risks (e.g., cancer, infertility, EHS) even below current exposure limits and advocate precautionary policy measures, including stricter limits and a 5G moratorium.

Impact of mobile phone-emitted non-ionizing electromagnetic radiation on parotid gland function: A comprehensive study

Research RF Safe Research Library Jan 1, 2025

This cross-sectional study of 104 university student volunteers assessed whether mobile phone-emitted non-ionizing electromagnetic radiation is associated with changes in parotid gland-related salivary measures. The authors report higher salivary flow rate and pH with longer mobile phone usage duration, along with side-related differences in albumin, IMA, and IMAR. The paper concludes that consistent exposure to mobile phone NIER and associated heat adversely affects parotid gland function and frames this as a health risk, while calling for further long-term research.

Skin Fibroblasts from Individuals Self-Diagnosed as Electrosensitive Reveal Two Distinct Subsets with Delayed Nucleoshuttling of the ATM Protein in Common

Research RF Safe Research Library Jan 1, 2025

This study reports on 26 adults self-diagnosed with electromagnetic hypersensitivity (EHS) who provided skin biopsies to generate primary fibroblast lines. The authors describe two EHS subsets based on questionnaire and DNA damage-related measures, and report delayed ATM nucleoshuttling after X-ray exposure in all samples, interpreted as impaired DNA repair signaling. They propose a molecular model linking EHS to ATM pathway dysfunction and suggest this could relate to increased cancer risk or accelerated aging.

Assessing RF EMF exposure in multiple microenvironments across ten European countries with a focus on 5G

Research RF Safe Research Library Jan 1, 2025

This exposure assessment measured environmental and auto-induced RF-EMF across more than 800 microenvironments in ten European countries, with a focus on 5G-related bands. Non-user environmental exposure was reported to be below international guideline values and similar to prior European research, while induced traffic substantially increased measured exposure, especially in uplink scenarios. The study also reports systematic differences by setting (cities vs villages) and by national precautionary limit policies.

Electromagnetic fields regulate iron metabolism: From mechanisms to applications

Research RF Safe Research Library Jan 1, 2025

This review synthesizes evidence that electromagnetic field (EMF) exposure is associated in the literature with changes in systemic and cellular iron metabolism, with reported effects varying by EMF parameters, exposure duration, and biological context. It proposes mechanistic pathways involving iron-containing proteins/tissues, membrane and ion channel modulation, and reactive oxygen species (ROS). The authors frame iron-metabolism modulation as relevant to both therapeutic applications and safety evaluation, while emphasizing inconsistencies and the need for standardized exposure protocols.

Single exposure to near-threshold 5G millimeter wave modifies restraint stress responses in rats

Research RF Safe Research Library Jan 1, 2025

In a rat experiment (n=59), a single 40-minute whole-body 28 GHz exposure at near-threshold WBA-SAR levels was evaluated under normal and heat conditions with restraint. After accounting for sham-related restraint stress, exposure was associated with increased serum-free corticosterone 1–3 days later, especially when rectal temperature rose by >1°C. Urinary catecholamines suggested an immediate inhibitory effect on stress response (notably noradrenaline), with heat amplifying effects and linking noradrenaline to tail surface temperature.

Effect of Occupational Exposure to Low-frequency Electromagnetic Fields on Cataract Development

Research RF Safe Research Library Jan 1, 2025

This cross-sectional epidemiologic study enrolled 100 employees of an electricity company to assess whether occupational low-frequency electromagnetic field exposure is associated with cataract development. Cataract frequency was higher in exposed versus non-exposed groups, and nuclear opacity grading differed significantly between groups. Within exposed workers, nuclear and posterior subcapsular cataract grades were associated with longer work experience, suggesting occupational exposure may be a risk factor, particularly for nuclear cataracts.

Electromagnetic wireless remote control of mammalian transgene expression

Research RF Safe Research Library Jan 1, 2025

This animal proof-of-concept study describes an engineered nanoparticle–cell interface (EMPOWER) enabling wireless regulation of transgene expression using a 1-kHz magnetic field. Chitosan-coated multiferroic nanoparticles reportedly generate intracellular ROS that activates KEAP1/NRF2 biosensors connected to ROS-responsive promoters. In a mouse model of type 1 diabetes, implanted engineered cells expressing an EMPOWER-controlled insulin system reportedly normalized blood glucose in response to a weak magnetic field.

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