Theta-gamma coupling in hippocampus during working memory deficits induced by low frequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2017
This mouse study examined whether 50 Hz, 1 mT electromagnetic field exposure affects working memory and hippocampal electrophysiology. The authors report reduced Y-maze working memory performance after 3 days of EMF exposure, accompanied by decreased hippocampal firing rates. They also report reduced theta and…
Vitamin C and Vitamin E Protected B and Balb/c-3T3 Cells from Apoptosis Induced by Intermittent 50Hz ELF-EMF Radiation.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed B cells and Balb/c-3T3 cells to intermittent 50 Hz power-line ELF-EMF and assessed apoptosis. The authors report that preincubation with vitamin C or vitamin E reduced apoptosis compared with the exposed group. They conclude that vitamins C and E have protective effects, with stronger…
Enhancement of osteogenic differentiation of rat adipose tissue-derived mesenchymal stem cells by zinc sulphate under electromagnetic field via the PKA, ERK1/2 and Wnt/β-catenin signaling pathways.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study examined rat adipose-derived mesenchymal stem cells exposed to zinc sulphate in the presence of an ELF electromagnetic field (50 Hz, 20 mT). The authors report increased osteogenic differentiation markers (gene expression, ALP activity, and calcium levels) under combined ZnSO4+EMF conditions,…
Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study used proteome-wide semi-quantitative mass spectrometry to assess molecular changes after short-term exposure to ELF (50 Hz), UMTS (2.1 GHz), and WiFi (5.8 GHz) in human and mouse cell types. The authors report that fewer than 1% of quantified proteins changed slightly in abundance and that…
The effects of human height and mass on the calculated induced electric fields at 50 Hz for comparison with the EMF Directive 2013/35/EU.
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RF Safe Research Library
Jan 1, 2017
This computational study examined how human height and mass influence calculated induced electric fields in the body from external 50 Hz electric and magnetic fields. Anatomically realistic human models derived from the MAXWEL phantom were varied across a range of heights and masses and used to simulate induced…
Efficacy of 50 Hz electromagnetic fields on human epidermal stem cell transplantation seeded in collagen sponge scaffolds for wound healing in a murine model.
Research
RF Safe Research Library
Jan 1, 2017
This animal study evaluated whether 50 Hz EMF exposure enhances wound healing after transplantation of human epidermal stem cells (ESC) seeded in collagen sponge scaffolds. Thirty-six nude mice with full-thickness wounds were assigned to control, ESC-only, or ESC+EMF groups (50 Hz, 5 mT, 60 min/day for 20 days). The…
Effects of extremely low frequency electromagnetic fields on in-vitro cellular cultures HeLa and CHO.
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RF Safe Research Library
Jan 1, 2016
This in-vitro study examined whether 50 Hz extremely low frequency electromagnetic fields affect proliferation in HeLa and CHO cell cultures. The abstract reports increased proliferation in exposed cells versus controls, with the largest reported increase under repetitive exposure at 2.49 mT (40 minutes every 12…
[Genic and non-genic regulation of low frequence pulsed electromagnetic fields on osteoblasts differentiation].
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study exposed rat calvarial osteoblasts to 50 Hz, 0.6 mT pulsed electromagnetic fields for 1.5 hours and measured early differentiation-related markers over 0–12 hours. The abstract reports increased ALP activity at 3 hours and time-dependent changes in ALP, Runx2, and OSX transcription and Runx2/OSX…
Effect of exposure to extremely low frequency magnetic fields on melatonin levels in calves is seasonally dependent
Research
RF Safe Research Library
Sep 18, 2015
This animal study measured salivary melatonin in 1–2 month old calves exposed to 50 Hz extremely low frequency magnetic fields in the hundreds of nT range. The authors report a season-dependent response: melatonin decreased with exposure in winter but increased in summer. They suggest future studies should consider…
Effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure on B6C3F1 mice
Research
RF Safe Research Library
May 5, 2015
This long-term animal study exposed mice to a 50 Hz magnetic field (500 mG) prenatally and then through 15.5 months of life to assess tumor-related outcomes and fertility-related measures. Exposed mice had lower body weights and showed no increase in liver or lung tumor incidence. However, exposed female mice had a…
The effects of different intensities, frequencies and exposure times of extremely low-frequency electromagnetic fields on the growth of Staphylococcus aureus and Escherichia coli O157:H7.
Research
RF Safe Research Library
Jan 1, 2015
This in vitro study examined whether extremely low-frequency electromagnetic fields (ELF-EMF) affect growth of Staphylococcus aureus and Escherichia coli O157:H7. Bacterial cultures were exposed to sinusoidal homogeneous ELF-EMF at 2 or 4 mT, with frequencies of 20, 40, or 50 Hz, for 1–6 hours, and CFU were compared…
Experimental model for ELF-EMF exposure: Concern for human health.
Research
RF Safe Research Library
Jan 1, 2015
This in vitro study examined whether extremely low frequency EMF exposure alters MCP-1 expression in several human cell lines. Cells were exposed to a 50 Hz sinusoidal field at 1 mT (rms), and the authors report that MCP-1 expression was modified in a cell-type-dependent manner. The findings are described as…
Assessment of the neurotoxic potential of exposure to 50Hz extremely low frequency electromagnetic fields (ELF-EMF) in naïve and chemically stressed PC12 cells
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Jan 1, 2014
This in vitro study tested acute (30 min) and sub-chronic (48 h) 50 Hz ELF-EMF exposure up to 1000 µT in naïve and chemically stressed PC12 cells. Across assays of Ca2+ homeostasis, ROS production, and membrane integrity, the study reports no consistent or measurable neurotoxic effects under the tested conditions.…
No effects of power line frequency extremely low frequency electromagnetic field exposure on selected neurobehavior tests of workers inspecting transformers and distribution line stations versus controls
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RF Safe Research Library
Jan 1, 2014
This study evaluated whether occupational 50 Hz ELF-EMF exposure near transformers and distribution power lines affects performance on several computer-based neurobehavior tests. Spot measurements found some electric-field locations above a national occupational standard, while all magnetic-field spots were below the…
Effect of ELF-EMF Exposure on Human Neuroblastoma Cell Line: a Proteomics Analysis
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Jan 1, 2014
This in vitro study exposed SH-SY5Y human neuroblastoma cells to a 2 mT, 50 Hz magnetic field for 3 hours and assessed protein expression using proteomics. The authors report that 189 proteins changed expression in exposed cells compared with controls, with PCA/clustering separating samples by condition. They…
Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway.
Research
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Jan 1, 2014
This in vitro study examined 50 Hz ELF-EMF effects on human T-type calcium channels expressed in HEK293 cells and on native T-type channels in primary cultured mouse cortical neurons. The authors report that ELF-EMF (0.2 mT) inhibited Cav3.1, Cav3.2, and Cav3.3 channel activity without changing Cav3.2 expression or…
P-selectin expression in a colon tumor model exposed by sinusoidal electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2013
This animal study evaluated whether sinusoidal magnetic field exposure alters P-selectin expression in a rat colon tumor model. Rats exposed to 50 Hz, 5 mT for 6 h/day for 8 months showed no statistically significant change in P-selectin expression by immunohistochemistry. The authors indicate that further in vitro…
Low-frequency electromagnetic fields do not alter responses of inflammatory genes and proteins in human monocytes and immune cell lines.
Research
RF Safe Research Library
Jan 1, 2012
This in vitro study examined whether low-frequency electromagnetic fields (a complex multiple waveform field and a 50 Hz sine wave) alter inflammatory gene and protein responses in human immune cells. Across time course experiments in THP-1 cells and primary monocytes/macrophages, the authors report no significant…
[Time effect of sinusoidal electromagnetic field on enhancing the maturation and mineralization of osteoblasts in vitro].
Research
RF Safe Research Library
Jan 1, 2011
This in vitro study exposed newborn rat calvarial osteoblasts to 50 Hz sinusoidal electromagnetic fields at 1.8 mT for different daily exposure times (0.5–3.0 h). The authors report inhibited osteoblast proliferation at longer exposure times, alongside increased differentiation markers (ALP activity) and…
Ohmic heating of peaches in the wide range of frequencies (50 Hz to 1 MHz).
Research
RF Safe Research Library
Jan 1, 2010
This engineering/food science study examined ohmic heating of peaches at 60 V/cm using bipolar pulses across frequencies from 50 Hz to 1 MHz. Heating time to a target temperature and multiple electrical properties were frequency-dependent, particularly for intact tissue. The authors report faster electro-thermal…
[Effects of 50 Hz sinusoidal magnetic field on Ca2+ release channel ryanodine receptor of sarcoplasmic reticulum vesicles].
Research
RF Safe Research Library
Jan 1, 2009
This in vitro study examined whether a 50 Hz sinusoidal magnetic field affects the sarcoplasmic reticulum calcium release channel RyR1. A 0.4 mT exposure for 30 minutes increased SR Ca2+ release rate and [(3)H]-ryanodine binding under NADH/NAD+ conditions. The authors also report increased NADH oxidation and…
Effects of extremely low frequency electromagnetic fields on testes in guinea pig.
Research
RF Safe Research Library
Jan 1, 2007
This animal study exposed 36 adult male guinea pigs to extremely low frequency electromagnetic fields at 5 Hz or 50 Hz and compared testosterone and testes tissue outcomes with sham/control conditions. After 5 days, the authors report a significant decrease in testosterone in exposed groups versus controls. They also…
Exposure to an additional alternating magnetic field affects comb building by worker hornets.
Research
RF Safe Research Library
Jan 1, 2007
This animal study reports that exposing worker oriental hornets in an artificial breeding box to an additional 50 Hz magnetic field (50–70 mGauss) altered comb construction compared with controls under only the terrestrial magnetic field. The abstract describes fewer cells and eggs, more deformed cell geometry, and…