Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway.
Research
RF Safe Research Library
Jan 1, 2014
This in vitro study examined 50 Hz ELF-EMF effects on human T-type calcium channels expressed in HEK293 cells and on native T-type channels in primary cultured mouse cortical neurons. The authors report that ELF-EMF (0.2 mT) inhibited Cav3.1, Cav3.2, and Cav3.3 channel activity without changing Cav3.2 expression or…
Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects
Research
RF Safe Research Library
Jan 1, 2013
This narrative review argues that non-thermal biological effects of extremely low and microwave frequency EMFs may be mediated by activation of voltage-gated calcium channels (VGCCs). It cites 23 studies in which VGCC blockers reportedly block or reduce diverse EMF effects and proposes downstream…
[The effect of weak low-frequency magnetic fields on the intracellular calcium-dependent proteinases of fish].
Research
RF Safe Research Library
Jan 1, 2013
This animal study examined in vivo and in vitro effects of weak, low-frequency magnetic fields described as having resonance parameters for calcium ions. The authors report a considerable decrease in activity of calcium-dependent proteinases (calpains) in fish skeletal muscle and brain following exposure. The…
[Effects of static magnetic field at different times on the proliferation and differentiation of osteoblasts in vitro].
Research
RF Safe Research Library
Jan 1, 2012
This in vitro study exposed newborn rat calvarial osteoblasts to a 3.9 mT static magnetic field for varying durations (0–4 hours). The authors report increased cell proliferation and markers of osteoblast differentiation and mineralization versus control, including higher ALP activity, calcium content, and…
[Effects of 50 Hz sinusoidal magnetic field on Ca2+ release channel ryanodine receptor of sarcoplasmic reticulum vesicles].
Research
RF Safe Research Library
Jan 1, 2009
This in vitro study examined whether a 50 Hz sinusoidal magnetic field affects the sarcoplasmic reticulum calcium release channel RyR1. A 0.4 mT exposure for 30 minutes increased SR Ca2+ release rate and [(3)H]-ryanodine binding under NADH/NAD+ conditions. The authors also report increased NADH oxidation and…
Head-to-head comparison of coronary plaque evaluation between multislice computed tomography and intravascular ultrasound radiofrequency data analysis.
Research
RF Safe Research Library
Jan 1, 2008
This study compared coronary plaque assessment by 64-slice multislice computed tomography (MSCT) with virtual histology intravascular ultrasound (VH IVUS) in 50 patients. The Agatston score on MSCT correlated moderately with calcium volume measured by VH IVUS, and MSCT plaque categories broadly reflected differences…
The influence of combined magnetic field on the fusion of plant protoplasts.
Research
RF Safe Research Library
Jan 1, 2007
This laboratory study examined whether a weak alternating magnetic field tuned to the cyclotron frequency of Ca2+ and K+ ions influences fusion of tobacco and soya protoplasts. The abstract reports a 2–3× increase in protoplast fusion frequency under exposure. It also reports involvement of calcium ions in induction…