Transcriptional response of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed rat primary hippocampal neurons to 3.0 GHz continuous-wave RF-EMF under low-SAR (minimal heating) and high-SAR (thermal) conditions and measured transcriptional responses by RNA sequencing. Twenty genes were significantly upregulated only in the high-SAR condition associated with a ~3.6°C…
Helmet Radio Frequency Phased Array Applicators Enhance Thermal Magnetic Resonance of Brain Tumors.
Research
RF Safe Research Library
Jan 1, 2024
This engineering study describes and simulates a helmet radio-frequency phased array applicator for Thermal Magnetic Resonance (ThermalMR), which combines MRI with targeted RF heating. Using EMF and temperature simulations in a phantom and human head model (including a modeled glioblastoma tumor volume), the authors…
Heating of metallic orthodontic devices during anti-aging treatment with vacuum and electromagnetic fields: In vitro study.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study evaluated heating of metallic orthodontic brackets/wires during an anti-aging treatment combining vacuum and electromagnetic fields (V-EMF). Using 20 resin-mouth setups covered with porcine muscle tissue, both beta-titanium and nickel-titanium wire groups showed about a 1.1°C temperature rise by…
Advanced Radio Frequency Applicators for Thermal Magnetic Resonance Theranostics of Brain Tumors.
Research
RF Safe Research Library
Jan 1, 2023
This engineering/simulation study evaluates RF applicator array designs for Thermal Magnetic Resonance (ThermalMR), which combines MRI with RF hyperthermia for brain tumor theranostics. Using EMF and temperature simulations at 7.0 T, 9.4 T, and 10.5 T, hybrid loop+SGBT dipole arrays are reported to provide superior…
Exposure to a 900 MHz electromagnetic field induces a response of the honey bee organism on the level of enzyme activity and the expression of stress-related genes.
Research
RF Safe Research Library
Jan 1, 2023
This animal study exposed one-day-old worker honey bees to 900 MHz RF-EMF at 12, 28, or 61 V/m for 15 minutes, 1 hour, or 3 hours, with an unexposed control group. The authors report changes in hemolymph enzyme activity and in expression of several stress-related genes following exposure. They state the pattern…
EMF Antenna Exposure on a Multilayer Human Head Simulation for Alzheimer Disease Treatments.
Research
RF Safe Research Library
Jan 1, 2022
This study uses HFSS/EMPro simulations to model a 64 MHz antenna exposure on a multilayer human head to match parameters previously used in neuronal culture experiments. The simulations report achieving up to 0.6 W/kg maximum SAR and approximately 0.4–0.6 W/kg across head layers with a 1 A peak current pulse. The…
Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.
Research
RF Safe Research Library
Jan 1, 2021
This review examines temperature-independent (non-thermal) effects of RF and microwave electromagnetic fields, emphasizing antiproliferative effects relevant to oncology. It summarizes preclinical and clinical literature on conventional RF hyperthermia and amplitude-modulated RF hyperthermia and argues that evidence…
Effect of Exposure to a Radiofrequency Electromagnetic Field on Body Temperature in Anesthetized and Non-Anesthetized Rats.
Research
RF Safe Research Library
Jan 1, 2020
This animal study examined whether anesthesia and body mass modify body temperature responses to 915 MHz RF exposure at 4 W/kg whole-body SAR for 8 hours. Non-anesthetized, free-moving rats showed no significant temperature change during exposure. In contrast, anesthetized rats showed marked temperature increases,…
Wideband Self-Grounded Bow-Tie Antenna for Thermal MR.
Research
RF Safe Research Library
Jan 1, 2020
This engineering study designed and tested a compact wideband self-grounded bow-tie RF antenna module for a whole-body 7.0 T MRI system, aiming to enable 1H/19F MRI, MR thermometry, and broadband RF thermal intervention. The authors report validated B1 efficiency measurements and phantom-based heating experiments…
Impact of electromagnetic fields on in vitro toxicity of silver and graphene nanoparticles.
Research
RF Safe Research Library
Jan 1, 2019
This in vitro study examined whether RF electromagnetic fields (900, 2400, 7500 MHz) modify the toxicity of silver and graphene nanoparticles in human fibroblast cultures. The authors report EMF-associated changes in cytotoxicity and ROS that depended on nanoparticle type, shape, and concentration, with the strongest…
Evaluation of MRI RF electromagnetic field induced heating near leads of cochlear implants.
Research
RF Safe Research Library
Jan 1, 2018
This simulation study evaluated RF-induced heating near cochlear implant leads during 1.5 T MRI using a transfer function method. Across studied configurations, the average temperature rise was 0.79 °C and the maximum was 2.80 °C at a whole-body average SAR of 2 W/kg. The authors report that lead trajectory and MRI…
Novel synthesis of MeO (Ni, Cu, La)@Nano-CoO from combination of complexation and impregnation in ultrasonic intervention for low temperature oxidation of toluene under microwave radiation.
Research
RF Safe Research Library
Jan 1, 2018
This engineering study describes synthesis of nano-metal binary oxide catalysts using complexation and impregnation with ultrasonic intervention for low-temperature catalytic oxidation of toluene under microwave radiation. The La-Co catalyst prepared with ultrasonic intervention is reported to have the best…
NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595
Research
RF Safe Research Library
Jan 1, 2018
This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…
C-phycocyanin extraction assisted by pulsed electric field from Artrosphira platensis.
Research
RF Safe Research Library
Jan 1, 2017
This engineering/food-processing study evaluates pulsed electric field (PEF) treatment of fresh Artrhospira platensis biomass to enhance aqueous extraction of C-phycocyanin. Extraction depended on electric field strength, treatment time, and application temperature, with higher temperatures reducing the required…
Quality stability and sensory attributes of apple juice processed by thermosonication, pulsed electric field and thermal processing.
Research
RF Safe Research Library
Jan 1, 2017
This study compared thermosonication, pulsed electric field, and thermal processing for preserving Royal Gala apple juice and evaluated sensory attributes and quality stability during 30 days of storage at 3°C and 20°C. Thermosonication and pulsed electric field produced juices with different taste compared with…
Effects of pH, temperature and pulsed electric fields on the turbidity and protein aggregation of ovomucin-depleted egg white.
Research
RF Safe Research Library
Jan 1, 2017
This laboratory study assessed how pH, temperature, and pulsed electric fields (PEF) affect turbidity and protein aggregation in ovomucin-depleted egg white solutions. Heating to 60°C for 10 minutes produced marked aggregation at several pH levels, while PEF caused some aggregation only at pH 5 and 7 under the…
Non-conductive and miniature fiber-optic imaging system for real-time detection of neuronal activity in time-varying electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2017
This paper describes a non-conductive, miniature fiber-optic imaging system designed to record neuronal activity in real time during repetitive, long-term time-varying EMF exposure. Using the system, the authors report that short exposures (
Antenna Design and SAR Analysis on Human Head Phantom Simulation for Future Clinical Applications.
Research
RF Safe Research Library
Jan 1, 2017
This study developed a mathematical and computer simulation model to analyze RF-EMF exposure in a human head phantom, motivated by potential therapeutic applications. The modeled exposure used a Yagi-Uda antenna at 64 MHz with SAR 0.6 W/kg and compared field distribution using one versus four antennas. COMSOL Bioheat…
The effect of a high frequency electromagnetic field in the microwave range on red blood cells.
Research
RF Safe Research Library
Jan 1, 2017
An in vitro study examined red blood cells exposed to an 18 GHz electromagnetic field and assessed uptake of nanospheres. The authors report that EMF exposure enabled nanosphere uptake into RBCs, with different translocation behavior for 23.5 nm versus 46.3 nm particles. Uptake was reported to increase with higher…
Radiation from wireless technology elevates blood glucose and body temperature in 40-year-old type 1 diabetic male.
Research
RF Safe Research Library
Jan 1, 2017
This case report describes a 40-year-old male with type 1 diabetes who reported repeated episodes of markedly elevated blood glucose associated with nearby microwave radiation from wireless technology, with decreases after exposure ended. In one episode, body temperature also increased, and both measures reportedly…
A wearable bluetooth LE sensor for patient monitoring during MRI scans.
Research
RF Safe Research Library
Jan 1, 2016
This engineering paper reports a prototype wearable patient-monitoring device that transmits vital-sign measurements via Bluetooth LE during MRI. Across 7 MRI acquisitions (25 minutes total), the authors report no Bluetooth packet loss, increased PPG noise during MRI, and no effect on temperature/humidity readings.…
Effects of Anatomical Differences on Electromagnetic Fields, SAR, and Temperature Change.
Research
RF Safe Research Library
Jan 1, 2016
This engineering study evaluates how anatomical/geometric differences affect MRI RF safety metrics. Simulations and a bovine-phantom experiment found that similar transmit B-field patterns can coincide with notably different peak SAR and temperature rise. The authors highlight challenges in using…
Subzero 12-hour Nonfreezing Cryopreservation of Porcine Heart in a Variable Magnetic Field.
Research
RF Safe Research Library
Jan 1, 2015
This animal organ-preservation study compared 12-hour porcine heart preservation at -3°C using a device generating a variable magnetic field versus conventional 4°C preservation. The subzero variable-magnetic-field condition showed higher myocardial ATP, lower lactate, and less mitochondrial ultrastructural damage…
Data supporting the role of electric field and electrode material on the improvement of the ageing effects in hydrogenated amorphous silicon solar cells.
Research
RF Safe Research Library
Jan 1, 2015
This Data in Brief article provides additional experimental data supporting a related study on mitigating ageing effects (Staebler-Wronski effect) in hydrogenated amorphous silicon solar cells. The associated method involves applying reverse bias stress and evaluating how temperature, electric field intensity,…
Effect of marination in gravy on the radio frequency and microwave processing properties of beef.
Research
RF Safe Research Library
Jan 1, 2015
This engineering/food science study measured dielectric constant (ε'), dielectric loss factor (ε″), and power penetration depth in beef and gravy preparations across 27–1,800 MHz and 20–130 °C. The dielectric properties generally decreased with increasing frequency, and penetration depth decreased with increasing…