Electromagnetic Field in Alzheimer's Disease: A Literature Review of Recent Preclinical and Clinical Studies.
Research
RF Safe Research Library
Jan 1, 2020
This literature review summarizes recent preclinical and clinical research on electromagnetic fields (EMF) in relation to Alzheimer's disease (AD). It describes AD pathology involving amyloid-beta accumulation and tau hyperphosphorylation and notes limitations of current symptomatic treatments. The authors report…
Evaluation of the neuroprotective effects of electromagnetic fields and coenzyme Q on hippocampal injury in mouse.
Research
RF Safe Research Library
Jan 1, 2019
This animal study tested whether 50 Hz EMF exposure and/or CoQ10 could protect against TMT-induced hippocampal injury in mature female mice. CoQ10 and CoQ10+EMF were associated with improved spatial memory and reduced histological markers of cell death, alongside increased antiapoptotic markers. EMF alone reportedly…
Microwave radiation leading to shrinkage of dendritic spines in hippocampal neurons mediated by SNK-SPAR pathway.
Research
RF Safe Research Library
Jan 1, 2018
This animal study exposed Wistar rats to microwave radiation (30 mW/cm for 6 minutes, three times per week for six weeks) and assessed cognition, hippocampal dendritic spines, ultrastructure, and SNK-SPAR pathway molecules. The authors report impaired spatial learning and memory, dendritic spine loss/shrinkage, and…
From the Cover: 2.45-GHz Microwave Radiation Impairs Hippocampal Learning and Spatial Memory: Involvement of Local Stress Mechanism-Induced Suppression of iGluR/ERK/CREB Signaling.
Research
RF Safe Research Library
Jan 1, 2018
This mouse study examined low-level 2.45 GHz continuous-wave microwave exposure for 2 hours/day over 15, 30, or 60 days. The authors report impaired learning and spatial memory performance on an 8-arm radial maze after exposure. They also report increased corticosterone and stress/inflammatory-related markers with…
No adverse effects detected for simultaneous whole-body exposure to multiple-frequency radiofrequency electromagnetic fields for rats in the intrauterine and pre- and post-weaning periods.
Research
RF Safe Research Library
Jan 1, 2017
This animal study exposed pregnant Sprague-Dawley rats and their offspring to simultaneous whole-body multifrequency RF signals spanning 800 MHz to 5.2 GHz. Exposure occurred 20 hours per day from gestational day 7 to weaning, with F1 offspring exposed up to 6 weeks of age. Across multiple endpoints including growth,…
Mobile phone use for 5 minutes can cause significant memory impairment in humans.
Research
RF Safe Research Library
Jan 1, 2017
This study assessed working memory before and after 5 minutes of mobile phone use using a brief computerized 10-word recall task. The experimental group showed worse performance immediately after phone use, with partial improvement 5 minutes later, while the control group improved across repeated tests without phone…
Theta-gamma coupling in hippocampus during working memory deficits induced by low frequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2017
This mouse study examined whether 50 Hz, 1 mT electromagnetic field exposure affects working memory and hippocampal electrophysiology. The authors report reduced Y-maze working memory performance after 3 days of EMF exposure, accompanied by decreased hippocampal firing rates. They also report reduced theta and…
Effects of Electromagnetic Radiation from Smartphones on Learning Ability and Hippocampal Progenitor Cell Proliferation in Mice.
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RF Safe Research Library
Jan 1, 2016
This mouse study examined chronic smartphone electromagnetic radiation exposure and its effects on spatial working memory and hippocampal progenitor cell proliferation. The authors report no significant differences in Y-maze spontaneous alternation or BrdU-labeled progenitor proliferation after exposure, but…
Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats
Research
RF Safe Research Library
Mar 19, 2015
This animal study exposed 108 male Sprague-Dawley rats to 900 MHz EMF (1 mW/cm2) or sham for 14 or 28 days (3 h/day). The authors report that 28-day exposure was associated with impaired spatial memory, BBB permeability damage, and ultrastructural changes in hippocampus and cortex. They also report increased mkp-1…
Memory performance, wireless communication and exposure to radiofrequency electromagnetic fields: A prospective cohort study in adolescents
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RF Safe Research Library
Jan 1, 2015
This prospective cohort study followed 439 adolescents for one year to assess whether wireless device use and estimated RF-EMF dose were associated with changes in memory performance. Higher cumulative mobile phone call duration and higher modeled RF-EMF brain and whole-body dose were associated with decreases in…
2.45 GHz Microwave Radiation Impairs Learning and Spatial Memory via Oxidative/Nitrosative Stress Induced p53-Dependent/Independent Hippocampal Apoptosis: Molecular Basis and Underlying Mechanism
Research
RF Safe Research Library
Jan 1, 2015
This animal study exposed male Swiss mice to 2.45 GHz continuous-wave microwave radiation for 2 hours/day over 15, 30, or 60 days. The authors report increased hippocampal oxidative/nitrosative stress and increased apoptosis in neuronal and nonneuronal hippocampal subfields. They also report duration-dependent…
Spatial learning, monoamines and oxidative stress in rats exposed to 900 MHz electromagnetic field in combination with iron overload.
Research
RF Safe Research Library
Jan 1, 2014
This animal study tested whether 900 MHz EMF exposure, alone or combined with brain iron overload, affects cognition and brain biochemistry in Long-Evans rats. EMF-exposed rats showed impairment in an object exploration task and changes in monoamine content (notably in the hippocampus), while other spatial…
Biodegradable shape memory nanocomposites with thermal and magnetic field responsiveness.
Research
RF Safe Research Library
Jan 1, 2013
This engineering study reports fabrication of a biodegradable PLLA shape-memory nanocomposite incorporating surface-modified Fe3O4 nanoparticles. The composite showed improved tensile/mechanical and shape-memory properties compared with PLLA, and shape recovery could be triggered by an alternating magnetic field.…
Effect of 60 minutes exposure to electromagnetic field on fecundity, learning and memory, speed of movement and whole body protein of the fruit fly Drosophila melanogaster.
Research
RF Safe Research Library
Jan 1, 2012
This animal study exposed Drosophila melanogaster to EMF from four electrical devices for 60 minutes and assessed fecundity, larval behavior, and protein patterns. The authors report no significant effect on adult fecundity, but report changes in larval learning/memory and movement speed, with the largest effects in…
Adverse effects of excessive mobile phone use.
Research
RF Safe Research Library
Jan 1, 2008
This cross-sectional questionnaire study surveyed 286 medical students about mobile phone use and health complaints. The abstract reports multiple self-reported symptoms (including impaired concentration, memory disturbances, sleeplessness, fatigue, and headache) and notes that 44.4% of respondents attributed their…
Polarization reversal in multiferroic TbMnO3 with a rotating magnetic field direction.
Research
RF Safe Research Library
Jan 1, 2007
This Physical Review Letters paper reports a method to reverse electric polarization in multiferroic TbMnO3 using a rotating magnetic-field direction, without applying an electric field or heat. The authors state that the direction of magnetic-field-induced polarization along the a axis is retained as a memory even…