Low-frequency electromagnetic fields promote hair follicles regeneration by injection a mixture of epidermal stem cells and dermal papilla cells.
Research
RF Safe Research Library
Jan 1, 2020
This animal study evaluated whether low-frequency EMF exposure affects bioengineered hair follicle generation in nude mice injected with a mixture of epidermal stem cells and dermal papilla cells. Histology (H&E) at 7 or 14 days suggested more hair follicle eruption and higher density of hair follicle-like structures…
The effect of electromagnetic fields on survival and proliferation rate of dental pulp stem cells.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study tested whether 50 Hz extremely low-frequency electromagnetic fields (0.5 or 1 mT) affect human dental pulp stem cell survival and proliferation. Using MTT and DAPI assays after 7 days of exposure (20 or 40 min/day), all exposed groups reportedly showed higher viability/proliferation than controls.…
Exploring the form- And time-dependent effect of low-frequency electromagnetic fields on maintenance of hippocampal long-term potentiation.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study developed an MEA-compatible magnetic stimulation device to deliver low-frequency EMFs during hippocampal LTP experiments without interrupting induction. The authors report that sine-wave LF-EMFs applied post-induction or as priming reduced fEPSP slope during LTP maintenance, with stronger effects…
Immune response of mollusk Onchidium struma to extremely low-frequency electromagnetic fields (ELF-EMF, 50 Hz) exposure based on immune-related enzyme activity and De novo transcriptome analysis.
Research
RF Safe Research Library
Jan 1, 2020
This animal study exposed the mollusk Onchidium struma to 50 Hz ELF-EMF at 100 μT or 500 μT for up to one week and assessed immune-related cell counts, enzyme activities, and transcriptomic changes. The 100 μT group showed increased total coelomocyte and spherulocyte density versus control and 500 μT, while some cell…
Extremely Low-Frequency Electromagnetic Fields Increase the Expression of Anagen-Related Molecules in Human Dermal Papilla Cells via GSK-3β/ERK/Akt Signaling Pathway.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study exposed human dermal papilla cells to 70 Hz extremely low-frequency electromagnetic fields at 5–100 G for four days. The abstract reports increased expression of several anagen-related molecules and increased proliferation, with 10 G described as the most potent condition. It also reports…
T-Cell Differentiation to T Helper 9 Phenotype is Elevated by Extremely Low-Frequency Electromagnetic Fields Via Induction of IL-2 Signaling.
Research
RF Safe Research Library
Jan 1, 2019
This in vitro study examined 60 Hz extremely low-frequency EMF exposure (0.8 mT) on CD4 T cells under Th9-polarizing conditions. The authors report increased Th9-associated responses including IL-9 secretion, transcription factor changes (including early GATA3), and increased STAT5/STAT6 phosphorylation alongside…
Low-frequency electromagnetic fields as an alternative to sanitize water of drinking systems in poultry production?
Research
RF Safe Research Library
Jan 1, 2019
This study tested pulsed low-frequency electromagnetic fields (up to 10,000 Hz; max 21 mT) as a potential alternative sanitation approach for poultry drinking water systems. LF-EMF exposure was linked to variable changes in culturable bacterial counts, with direction depending on system type and some early…
Geobacter sulfurreducens-inoculated bioelectrochemical system reveals the potential of metabolic current in defining the effect of extremely low-frequency electromagnetic field on living cells.
Research
RF Safe Research Library
Jan 1, 2019
This laboratory study exposed a Geobacter sulfurreducens-inoculated bioelectrochemical system to 0–128 Gauss extremely low-frequency electromagnetic fields. The authors report increased and oscillatory metabolic current under ELF-EMF exposure, with dose-dependent effects and a linear relationship between oscillation…
Synergistic effect of rice bran extract and extremely low-frequency electromagnetic fields on dermal papilla/melanocytes in melanogenesis.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study used a 3D dermal papilla-like tissue model containing dermal papilla cells and melanocytes to assess melanogenesis after rice bran extract (RBE), extremely low-frequency EMF, or their combination. The combined RBE/EMF condition showed higher tyrosinase activity, increased melanogenesis-related…
Effects of Fifty-Hertz Electromagnetic Fields on Granulocytic Differentiation of ATRA-Treated Acute Promyelocytic Leukemia NB4 Cells.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study examined whether 50 Hz, 2 mT extremely low-frequency electromagnetic fields affect ATRA-driven granulocytic differentiation in NB4 acute promyelocytic leukemia cells. The authors report reduced proliferation and enhanced maturation/differentiation markers with ELF-EMF exposure. They also report…
Case-Control Study on Occupational Exposure to Extremely Low-Frequency Electromagnetic Fields and the Association with Meningioma.
Research
RF Safe Research Library
Jan 1, 2018
This case-control analysis assessed occupational extremely low-frequency electromagnetic field (ELF-EMF) exposure and meningioma using the INTEROCC ELF-EMF job-exposure matrix. Cumulative, average, and maximum job exposure metrics were evaluated. The study reports no increased meningioma risk in any exposure…
Extremely low-frequency electromagnetic fields accelerates wound healing modulating MMP-9 and inflammatory cytokines.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study used a scratch wound model in human immortalized keratinocytes (HaCaT) to examine effects of extremely low-frequency electromagnetic fields (ELF-EMF). ELF-EMF exposure was reported to accelerate wound closure compared with sham and to increase inflammatory cytokine expression/release. The authors…
Effect of extremely low-frequency electromagnetic fields on antioxidant activity in the human keratinocyte cell line NCTC 2544.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed human keratinocyte cells (NCTC 2544) to 50 Hz ELF-EMF at 0.25–2 G and assessed oxidative stress-related endpoints. Significant increases in ROS were reported at 0.5 and 1 G, with associated short-term changes in antioxidant and lipid peroxidation markers. The authors report that…
Effect of electromagnetic fields and antioxidants on the trace element content of rat teeth.
Research
RF Safe Research Library
Jan 1, 2017
This animal study examined whether extremely low-frequency electromagnetic fields (ELF-EMFs) from a high-voltage source alter trace element concentrations in rat teeth and whether antioxidants (melatonin and glutathione) modify these changes. Rats were exposed 8 hours/day for 26 or 52 days, with separate sham…
Alterations of Immune Parameters on Trichoplusia ni (Lepidoptera: Noctuidae) Larvae Exposed to Extremely Low-Frequency Electromagnetic Fields.
Research
RF Safe Research Library
Jan 1, 2017
This animal study exposed Trichoplusia ni larvae to 60 Hz, 2.0 mT ELF-EMF for 24, 48, or 72 hours and assessed immune parameters and fertility. The abstract reports no effect on life cycle and fertility after 24 hours, but several immune-related measures changed after 48–72 hours, including reduced hemolymph protein…
Quantum mechanical model for the anticarcinogenic effect of extremely-low-frequency electromagnetic fields on early chemical hepatocarcinogenesis.
Research
RF Safe Research Library
Jan 1, 2017
This study develops a quantum-mechanical radical pair mechanism model to examine how an extremely-low-frequency electromagnetic field (ELF-EMF) might influence early chemical hepatocarcinogenesis in rats. The model evaluates singlet-state recombination and quantum yield under a low magnetic field effect, proposing…
Effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure on B6C3F1 mice
Research
RF Safe Research Library
May 5, 2015
This long-term animal study exposed mice to a 50 Hz magnetic field (500 mG) prenatally and then through 15.5 months of life to assess tumor-related outcomes and fertility-related measures. Exposed mice had lower body weights and showed no increase in liver or lung tumor incidence. However, exposed female mice had a…
[Influence of Low-Frequency Electromagnetic Field on DNA Molecules in Water Solutions].
Research
RF Safe Research Library
Jan 1, 2015
This in vitro study reports that hepatitis B and C virus DNA amplicons in water solutions produced a chemiluminescence-registered signal after exposure to low-frequency electromagnetic fields (3–30 Hz; 24–40 A/m). The strongest reported effect occurred at 9 Hz, alongside an observed change in the DNA hydration shell.…
The effects of different intensities, frequencies and exposure times of extremely low-frequency electromagnetic fields on the growth of Staphylococcus aureus and Escherichia coli O157:H7.
Research
RF Safe Research Library
Jan 1, 2015
This in vitro study examined whether extremely low-frequency electromagnetic fields (ELF-EMF) affect growth of Staphylococcus aureus and Escherichia coli O157:H7. Bacterial cultures were exposed to sinusoidal homogeneous ELF-EMF at 2 or 4 mT, with frequencies of 20, 40, or 50 Hz, for 1–6 hours, and CFU were compared…
Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway.
Research
RF Safe Research Library
Jan 1, 2014
This in vitro study examined 50 Hz ELF-EMF effects on human T-type calcium channels expressed in HEK293 cells and on native T-type channels in primary cultured mouse cortical neurons. The authors report that ELF-EMF (0.2 mT) inhibited Cav3.1, Cav3.2, and Cav3.3 channel activity without changing Cav3.2 expression or…
Low-frequency electromagnetic fields do not alter responses of inflammatory genes and proteins in human monocytes and immune cell lines.
Research
RF Safe Research Library
Jan 1, 2012
This in vitro study examined whether low-frequency electromagnetic fields (a complex multiple waveform field and a 50 Hz sine wave) alter inflammatory gene and protein responses in human immune cells. Across time course experiments in THP-1 cells and primary monocytes/macrophages, the authors report no significant…
Proteomic analysis in human fibroblasts by continuous exposure to extremely low-frequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2007
This in vitro study examined whether continuous extremely low-frequency electromagnetic fields (3 Hz, 4 mT for 3 hours) alter protein expression in human fibroblast cells using proteomics. The authors report that some protein expressions differed between exposed and sham cells. They identify reduced expression (about…