Measurement of creatine kinase reaction rate in human brain using magnetization transfer image-selected in vivo spectroscopy (MT-ISIS) and a volume ³¹P/¹H radiofrequency coil in a clinical 3-T MRI system.
Research
RF Safe Research Library
Jan 1, 2011
This paper describes a new magnetization transfer 31P MRS approach (MT-ISIS) for measuring the creatine kinase forward reaction rate in the human brain using a volume 31P/1H RF coil on a clinical 3-T MRI system. The method aims to reduce acquisition time (30 min), avoid scalp muscle contamination, improve RF…
Correction of main and transmit magnetic field (B0 and B1) inhomogeneity effects in multicomponent-driven equilibrium single-pulse observation of T1 and T2.
Research
RF Safe Research Library
Jan 1, 2011
This methods paper addresses how B0 (main field) and B1 (transmit field) inhomogeneities can bias SPGR and bSSFP steady-state MRI signals used for multicomponent T1/T2 relaxometry and myelin water analysis. It describes using DESPOT1-HIFI to calibrate flip angles and adding a B0-related parameter with multiple…
In vivo quantification of contrast agent concentration using the induced magnetic field for time-resolved arterial input function measurement with MRI.
Research
RF Safe Research Library
Jan 1, 2008
This Medical Physics article presents a phase-based MRI method to quantify paramagnetic contrast agent concentration by inverting susceptibility-induced magnetic field shifts, aiming to improve arterial input function (AIF) measurement in DCE-MRI. After in vitro validation, the approach was applied in vivo in 14…