This review discusses epidemiological and mechanistic reports linking EMF exposure with oxidative stress and disease risk, and introduces an Electromagnetic Pathogenesis (EMP) conceptual model. The model proposes that non-ionizing EMFs increase mitochondrial electron leakage via electron tunneling, raising free radical production and oxidative stress. The authors argue oxidative stress is a primary mechanism connecting EMF exposure to cancer, cardiovascular, neurodevelopmental/neurodegenerative diseases, and behavioral/reproductive effects, and suggest reducing exposure may lower risk.

This animal study used metabolomics to assess metabolic changes in male Drosophila melanogaster exposed to 3.5 GHz RF-EMF at 0.1, 1, and 10 W/m². It reports disruptions in four metabolic pathways and 34 differential metabolites, with significant decreases in several metabolites including GABA, glucose-6-phosphate, and AMP. The authors interpret the findings as suggesting RF-EMF-related metabolic disturbance, while noting no clear dose-dependent pattern.

This 2025 review summarizes historical and modern literature on how bacteria may adapt to radiofrequency electromagnetic fields from common sources such as mobile phones and Wi-Fi. It argues that RF-EMF exposure can influence bacterial survival mechanisms and could potentially compromise therapeutic interventions by promoting increased resistance. The authors frame these possibilities as a public health concern and call for continued research and precaution.

This rat study assessed whether alpha-lipoic acid (ALA) modifies liver effects from extremely low-frequency magnetic field (ELF-MF) exposure. ELF-MF exposure (2 mT, 4 hours/day for 30 days) was associated with increased liver pathology and higher apoptosis markers (TUNEL, caspase-3) compared with other groups. ALA reduced several histopathological changes and lowered TUNEL/caspase-3, but did not improve fibrosis or biliary proliferation.

This controlled laboratory study examined sex-specific behavioral responses of juvenile shore crabs to magnetic fields intended to represent submarine power cable EMFs. Females showed consistent attraction to EMF-exposed zones across 500–3,200 μT exposures, whereas males showed no consistent spatial preference. The authors suggest such sex-specific sensitivity could disrupt female-driven behaviors relevant to migration and reproduction, with potential ecological implications.

This animal study exposed zebrafish embryos to static electromagnetic fields for 63 days post-hatching across aquariums positioned 30–99 cm from the source, with an EMF-free control. The abstract reports strong shifts in sex distribution (including 100% female at the closest distance), markedly reduced survival in exposed groups, and histological liver and gonadal damage. The authors frame the findings as evidence of potential ecological risk via disrupted sex ratios and compromised health.

This retrospective observational study analyzed Murmuras app data from 1074 participants in 2022 to examine demographic differences in smartphone use and nocturnal smartphone inactivity duration (a proxy for sleep-related behavior). Nighttime smartphone use increased, especially for social media and entertainment, and usage patterns varied by gender, age, education, and employment status. Most demographic groups showed no significant correlation between usage duration and nocturnal inactivity, although some subgroups showed correlations in either direction. The authors frame excessive nighttime smartphone use as potentially adverse for sleep and link this behavioral exposure to electromagnetic fields with sleep health risks.

This animal study exposed mice to 2.45 GHz electromagnetic fields daily for up to 5 months and assessed liver effects using serum tests, lipidomics, histology, and single-cell/spatiotemporal transcriptomics. The authors report that hepatic cell types differed in sensitivity, with hepatocytes, endothelial cells, and monocytes showing notable transcriptomic disruptions. Reported changes involved lipid metabolism and immune regulation and were spatially enriched in peri-portal liver regions. The authors frame the findings as evidence of significant biological impacts on the liver from long-term EMF exposure.

This ex-vivo experimental study tested whether electromagnetic fields from a commercial hair dryer affect microleakage of class V dental amalgam restorations in 100 extracted human teeth. Several exposure groups showed significantly higher dye-penetration microleakage scores than the unexposed control, while one exposure condition did not differ from control. The authors conclude that hair-dryer EMF exposure can increase microleakage and potentially compromise restoration integrity.

This blinded, two-year study examined whether RF-EMF exposure at 2.4 and 5.8 GHz affects pollinator visitation to Salvia and Lavandula. The authors report no significant effect on honey bee visitation rates. They report a significant reduction in bumble bee visits per observation period under RF-EMF exposure, which they frame as a potential risk warranting further long-term research.

This paper proposes a new methodology to better assess indoor RF-EMF exposure in buildings near telecommunication base station antennas by refining measurement-point selection. Implemented in four multi-storey buildings in Natal, Brazil, indoor electric field peaks and averages were reported to be substantially higher than ground-level measurements. Although the highest indoor levels remained below ICNIRP recommended limits, the authors argue current regulatory evaluation methods may underestimate indoor exposure in certain building locations.

This animal study examined thyroid histomorphometry in juvenile male Wistar rats after 2 weeks of 5G EMF exposure (3.5 GHz, 1.5 V/m). Exposed rats showed larger follicle and colloid areas and a significantly lower Thyroid Activation Index, which the authors interpret as thyroid hypoactivity. The authors suggest this may represent a potential health risk and call for further work including hormone assays and mechanistic studies.

This narrative review discusses low-intensity RF-EMF exposure, primarily from mobile phones, with a focus on thermoregulation and energy homeostasis. It reports that many rodent studies at 900 MHz describe cold-like thermoregulatory and behavioral responses and molecular findings suggestive of WAT browning, while BAT transcriptional changes typical of cold exposure were not observed. The authors indicate short-term adaptations may not disrupt homeostasis, but emphasize uncertainty about long-term consequences and call for further research, including at 5G-relevant frequencies.

This animal study measured core body temperature in free-moving male and female Sprague Dawley rats during and after 3-hour exposure to 1.95 GHz RF-EMF at multiple whole-body average SAR levels. A measurable thermal response was reported at 4 W/kg, while lower SAR conditions showed smaller or no significant temperature increases. The authors note that temperature dropped quickly after exposure ended, implying post-exposure measurements may underestimate peak heating.

This narrative review discusses biological mechanisms and reported health effects of anthropogenic extremely low frequency (ELF) and wireless communication (WC) electromagnetic fields. It highlights oxidative stress and DNA damage as key mechanistic endpoints and proposes an IFO-VGIC pathway linking EMF exposure to ROS overproduction and cellular dysfunction. The authors interpret the broader literature as indicating risks (e.g., cancer, infertility, EHS) even below current exposure limits and advocate precautionary policy measures, including stricter limits and a 5G moratorium.