Archive

75 posts

Showing results for: DNA

Development and Testing of a Novel Whole-body Exposure System for Investigative Studies of Radiofrequency Radiation in Rodents (NIEHS)

Research RF Safe Research Library Jan 1, 2025

This NIEHS report describes the development and testing of a flexible whole-body radiofrequency radiation exposure system for rats and mice using updated signals relevant to wireless technologies. In 5-day studies with CDMA- and GSM-modulated signals, no visible behavioral responses were observed and comet assays…

Role of visual and non-visual opsins in blue light-induced neurodegeneration in Drosophila melanogaster

Research RF Safe Research Library Jan 1, 2025

This animal study used Drosophila knockout lines to examine whether visual (Rh1) versus non-visual (Rh7) opsins contribute to blue-light-associated neural damage. Flies were continuously exposed to 488 nm blue light from egg deposition to 20 days, and brain DNA damage and vacuolisation were assessed. The study…

Radiofrequency radiation-induced gene expression

Research RF Safe Research Library Jan 1, 2025

This review summarizes studies reporting radiofrequency radiation (RFR)-associated changes in gene expression across biological systems. Reported affected genes relate to cellular stress responses, oxidative processes, apoptosis, DNA damage detection/repair, protein repair, and neural function regulation. The authors…

Male Reproductive and Cellular Damage After Prenatal 3.5 GHz Radiation Exposure: One-Year Postnatal Effects

Research RF Safe Research Library Jan 1, 2025

This animal study examined whether prenatal exposure to 3.5 GHz radiofrequency radiation (2 hours/day) affects male reproductive outcomes later in life. Male rat offspring assessed at 12 months showed multiple adverse testicular and cellular findings in exposed groups versus sham controls, including impaired…

Microwave and RF Exposure-Induced Molecular and Genetic Alterations

Research RF Safe Research Library Jan 1, 2025

This review discusses recent studies on microwave and RF exposure and their reported impacts on molecular and cytogenetic materials. It states there is growing evidence that RF exposure can induce DNA damage at levels considered safe by current standards, and cites newly reported genetic alterations in rat cancers…

Altered development in rodent brain cells after 900 MHz radiofrequency exposure

Research RF Safe Research Library Jan 1, 2025

This animal and in vitro study examined non-thermal 900 MHz RF-EMF exposure during prenatal and postnatal development at 0.08 and 0.4 W/kg SAR. The authors report changes consistent with altered neurodevelopment, including reduced BDNF, reduced in vivo cell proliferation, and disrupted synaptic balance in rat pup…

Oxidative stress and testicular damage induced by chronic exposure to 35.5 GHz millimeter wave radiation in male Wistar rats

Research RF Safe Research Library Jan 1, 2025

This randomized controlled animal study examined chronic 35.5 GHz millimeter wave exposure in male Wistar rats (2 hours/day for 60 days) compared with control and sham groups. The exposed group showed reduced sperm count and viability along with testicular histopathological changes. Oxidative stress markers shifted…

Impact of in vitro exposure to 5G-modulated 3.5 GHz fields on oxidative stress and DNA repair in skin cells

Research RF Safe Research Library Jan 1, 2025

This in vitro study tested whether 5G-modulated 3.5 GHz RF-EMF exposure affects oxidative stress and DNA repair in human skin cells. Under acute exposure conditions (up to 24–48h) at SARs up to 4 W/kg, the authors report no significant changes in ROS markers, no adaptive response to oxidative challenge, and no…

Exposure of human lymphocytes to sweeping-frequency extremely low frequency magnetic field

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed human umbilical cord blood lymphocytes to a sinusoidal sweeping-frequency ELF magnetic field (3–26 Hz) for 48 hours at amplitudes from 6 to 24 μT. It reports no statistically significant effects on DNA damage/repair foci or apoptosis measures overall. A non-significant trend at 8 μT showed…

A scoping review and evidence map of radiofrequency field exposure and genotoxicity: assessing in vivo, in vitro, and epidemiological data

Research RF Safe Research Library Jan 1, 2025

This scoping review and evidence map (PRISMA-ScR) summarizes over 500 studies on RF-EMF exposure and genotoxicity across in vitro, in vivo, and epidemiological research. The authors report a higher proportion of significant DNA damage findings in in vivo and epidemiological studies than in vitro studies, with DNA…

Genotoxic and histopathological effects of 6 GHz radiofrequency electromagnetic radiation on rat liver tissue

Research RF Safe Research Library Jan 1, 2025

This animal experiment exposed adult male rats to 6 GHz RF-EMR (0.065 W/kg) for 4 hours/day over 42 days and compared them with sham controls. The exposed group showed higher comet assay genotoxicity metrics, though not statistically significant, and more prominent liver histopathological changes (e.g., portal…

Investigation of the Effects of 2.45 GHz Near-Field EMF on Yeast

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed yeast suspensions to 2.45 GHz near-field microwave radiation at 2 cm and 4 cm for 20 or 60 minutes. It reports oxidative-stress-related changes (reduced antioxidant activity with increased membrane permeability) after 20 minutes at 2 cm, an effect not reproduced by conventional heating.…

Exposure to 26.5 GHz, 5G modulated and unmodulated signal, does not affect key cellular endpoints of human neuroblastoma cells

Research RF Safe Research Library Jan 1, 2025

This in vitro study examined whether 26.5 GHz millimeter-wave exposure (continuous wave and 5G-modulated) affects key cellular endpoints in human neuroblastoma cells. Cells were exposed for 3 hours at SAR 1.25 W/kg using a reverberation-chamber system, with assessments including cell cycle and DNA damage. The study…

A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses biological mechanisms and reported health effects of anthropogenic extremely low frequency (ELF) and wireless communication (WC) electromagnetic fields. It highlights oxidative stress and DNA damage as key mechanistic endpoints and proposes an IFO-VGIC pathway linking EMF exposure to…

5G-exposed human skin cells do not respond with altered gene expression and methylation profiles

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed human skin cells (fibroblasts and keratinocytes) to 5G-band electromagnetic fields for 2 hours and 48 hours using a fully blinded design. Exposures were up to ten times permissible limits, with sham exposure as a negative control and UV exposure as a positive control. The study reports…

Skin Fibroblasts from Individuals Self-Diagnosed as Electrosensitive Reveal Two Distinct Subsets with Delayed Nucleoshuttling of the ATM Protein in Common

Research RF Safe Research Library Jan 1, 2025

This study reports on 26 adults self-diagnosed with electromagnetic hypersensitivity (EHS) who provided skin biopsies to generate primary fibroblast lines. The authors describe two EHS subsets based on questionnaire and DNA damage-related measures, and report delayed ATM nucleoshuttling after X-ray exposure in all…

Exploring the impact of environmental factors on male reproductive health through epigenetics

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses how environmental factors may affect male reproductive health through epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation. It reports that electromagnetic radiation, particularly from mobile phones and wireless…

Effects of 700MHz radiofrequency radiation (5G lower band) on the reproductive parameters of female Wistar rats

Research RF Safe Research Library Jan 1, 2025

This animal study examined short- and long-term 700 MHz (lower-band 5G) radiofrequency exposure in female Wistar rats, comparing control, sham, and exposed groups. It reports no DNA damage and no change in estrous cycle length, but increased ovarian oxidative stress markers in exposed animals. Long-term exposure was…

Effect of electromagnetic field radiation on transcriptomic profile and DNA methylation level in pig conceptuses during the peri-implantation period

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed pig conceptuses (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed transcriptomic and DNA methylation changes. The authors report altered expression of 21 protein-coding transcripts and an approximately 16-fold increase in genomic DNA methylation, with promoter methylation…

The effects of radiofrequency radiation on male reproductive health and potential mechanisms (Review)

Research RF Safe Research Library Jan 1, 2025

This narrative review summarizes human and animal research on radiofrequency (RF) radiation exposure (e.g., mobile phones, Wi‑Fi, occupational sources) and male reproductive outcomes. It reports that the literature links RF exposure with reduced sperm quality and increased DNA damage, often alongside oxidative stress…

Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.

Research RF Safe Research Library Jan 1, 2025

This in vitro study examined ELF-EMF effects in normal cybrids and NARP cybrids carrying a pathogenic MT-ATP6 mtDNA mutation mixture. ELF-EMF did not alter mtDNA copy number or the wild-type-to-mutant mtDNA ratio, but it increased mtDNA transcription and multiple markers of mitochondrial function in NARP cybrids,…

Corrigendum to "Effects of radiofrequency electromagnetic field (RF-EMF) exposure on male fertility: A systematic review of experimental studies on non-human mammals and human sperm in vitro" [Environ. Int. 185 (2024) 108509]

Research RF Safe Research Library Jan 1, 2025

This 2025 corrigendum relates to a systematic review of experimental RF-EMF exposure studies on non-human mammals and human sperm in vitro. The text reports an upgrade to high certainty for the key endpoint that male RF-EMF exposure causes a significant reduction in pregnancy rate when exposed males are mated. It…

Electric and Magnetic Field Technologies in Agriculture: Plant Responses, Experimental Limitations, and Future Directions

Research RF Safe Research Library Jan 1, 2024

This narrative review discusses how electric and magnetic field technologies are applied in agriculture and how plants may respond. It proposes a model to explain potential mechanistic convergence between electric and magnetic field effects. The review highlights several suggested mechanisms, including membrane…

The In Vitro Enhancement of Retinal Cell Viability via mA and mC RNA Methylation-Mediated Changes in the Levels of Heme Oxygenase (HO-1) and DNA Damage Repair Molecules Using a 50 Hz Sinusoidal Electromagnetic Field (EMF).

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested a 50 Hz, 1.3 mT sinusoidal electromagnetic field applied for 15 or 30 minutes to ARPE-19 retinal pigment epithelial cells and RGC-5 retinal ganglion cells. The authors report improved proliferative and migratory capacity after EMF exposure, alongside increased HO-1 and altered RNA…

A Pilot Study Evaluating the Feasibility and Efficacy of an In-Home Resonance-Based Electromagnetic Field Protection Device on Improving Markers of Health and Cognitive Function Among a Sample of Healthy Adults.

Research RF Safe Research Library Jan 1, 2024

This single-arm 12-week pilot/feasibility study enrolled 25 relatively healthy adults to evaluate an in-home resonance-based EMF protection device (BluShield). The abstract reports high compliance and no adverse events, with modest improvements in self-reported health, several cognitive questionnaire domains, and…

← Prev Page 2 / 3 Next →