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Lipidomic alteration and stress-defense mechanism of soil nematode Caenorhabditis elegans in response to extremely low-frequency electromagnetic field exposure.

Research RF Safe Research Library Jan 1, 2019

This animal (nematode) study exposed Caenorhabditis elegans to 50 Hz, 3 mT extremely low-frequency EMF and assessed multi-omics responses. The authors report significant lipidomic, proteomic, and transcriptomic alterations, including increased triacylglycerols. Pathway analyses suggest disrupted lipid metabolism,…

Effect of Extremely Low Frequency Electromagnetic Fields on Expression of T-bet and GATA-3 Genes and Serum Interferon-γ and Interleukin-4.

Research RF Safe Research Library Jan 1, 2019

This rat study examined 50 Hz ELF-EMF exposure (1–2000 μT) for 60 days and measured Th-related gene expression and cytokines in an HSA-stimulated immune model. Splenic T-bet and GATA-3 mRNA expression decreased at 1 and 100 μT. Serum IFN-γ and IL-4 were significantly decreased in the 100 μT group only before HSA…

Impact of electromagnetic fields on in vitro toxicity of silver and graphene nanoparticles.

Research RF Safe Research Library Jan 1, 2019

This in vitro study examined whether RF electromagnetic fields (900, 2400, 7500 MHz) modify the toxicity of silver and graphene nanoparticles in human fibroblast cultures. The authors report EMF-associated changes in cytotoxicity and ROS that depended on nanoparticle type, shape, and concentration, with the strongest…

Electromagnetic field treatment increases purinergic receptor P2X7 expression and activates its downstream Akt/GSK3β/β-catenin axis in mesenchymal stem cells under osteogenic induction.

Research RF Safe Research Library Jan 1, 2019

This study examined how electromagnetic field (EMF) treatment influences osteogenic differentiation mechanisms in human bone marrow mesenchymal stem cells and tested a combined therapy in an ovariectomized rat osteoporosis model. The authors report that EMF exposure increased P2X7 receptor expression during…

The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect.

Research RF Safe Research Library Jan 1, 2019

This animal and in vitro study evaluated sinusoidal electromagnetic field (SEMF) exposure combined with VEGF in rat mesenchymal stem cells and in a rat cranial defect model using rBMSC-laden PCL/HA scaffolds. The authors report increased osteogenic and endothelial marker expression with SEMF and VEGF, with a slight…

The effects of the electromagnetic fields on the biochemical components, enzymatic and non-enzymatic antioxidant systems of tea L.

Research RF Safe Research Library Jan 1, 2019

This laboratory study examined how electromagnetic field (EMF) treatment affects biochemical and antioxidant-related components in tea samples, including flavonoid markers measured by HPLC. The abstract reports that 30-minute exposures generally increased several flavonoids compared with 60-minute exposures, with the…

Evaluation of the effects of extremely low frequency electromagnetic field on the levels of some inflammatory cytokines in post-stroke patients.

Research RF Safe Research Library Jan 1, 2019

This study evaluated whether adding therapeutic extremely low frequency electromagnetic field (ELF-EMF) treatment to a rehabilitation program affects inflammatory cytokine activity in post-stroke patients. Following ELF-EMF treatment, IL-1β plasma levels and IL-1β mRNA expression increased, and IL-2 plasma levels…

T-Cell Differentiation to T Helper 9 Phenotype is Elevated by Extremely Low-Frequency Electromagnetic Fields Via Induction of IL-2 Signaling.

Research RF Safe Research Library Jan 1, 2019

This in vitro study examined 60 Hz extremely low-frequency EMF exposure (0.8 mT) on CD4 T cells under Th9-polarizing conditions. The authors report increased Th9-associated responses including IL-9 secretion, transcription factor changes (including early GATA3), and increased STAT5/STAT6 phosphorylation alongside…

Emerging medical applications based on non-ionizing electromagnetic fields from 0 Hz to 10 THz.

Research RF Safe Research Library Jan 1, 2019

This review discusses medical applications of non-ionizing electromagnetic fields spanning 0 Hz to the THz range, focusing mainly on therapeutic uses and mentioning few diagnostic approaches. It reports that current EMF-based methods generally have limited clinical impact and are not expected to replace conventional…

Evaluation of the Validity of a Nonlinear J-Shaped Dose-Response Relationship in Cancers Induced by Exposure to Radiofrequency Electromagnetic Fields.

Research RF Safe Research Library Jan 1, 2019

This review discusses the controversial evidence on mobile phone RF-EMF exposure and brain cancer. The authors argue that exposure magnitude may be a key factor contributing to inconsistent findings. They discuss evidence supporting a nonlinear J-shaped dose-response relationship for RF-EMF-related carcinogenesis.

[Electromagnetic field in the environment - estimation methods and monitoring].

Research RF Safe Research Library Jan 1, 2019

This paper discusses the legal context for environmental EMF measurements and describes methods for estimating EMF intensity from multiple sources, particularly cellular base stations. It presents an engineering concept for mobile EMF monitoring and reports verification testing of the measurement setup. Field…

Low-frequency electromagnetic fields as an alternative to sanitize water of drinking systems in poultry production?

Research RF Safe Research Library Jan 1, 2019

This study tested pulsed low-frequency electromagnetic fields (up to 10,000 Hz; max 21 mT) as a potential alternative sanitation approach for poultry drinking water systems. LF-EMF exposure was linked to variable changes in culturable bacterial counts, with direction depending on system type and some early…

[The reaction of the circulatory system to stress and electromagnetic fields emitted by mobile phones - 24-h monitoring of ECG and blood pressure].

Research RF Safe Research Library Jan 1, 2019

In a worker sample undergoing 24-hour ECG and ambulatory blood pressure monitoring, higher self-reported daily mobile phone use (>60 minutes) was associated with higher systolic blood pressure in office measurement and at night. Higher occupational stress was associated with higher systolic and diastolic blood…

Residential exposure to ultra high frequency electromagnetic fields emitted by Global System for Mobile (GSM) antennas and amyotrophic lateral sclerosis incidence: A geo-epidemiological population-based study.

Research RF Safe Research Library Jan 1, 2019

This geo-epidemiological population-based study in Limousin (France) assessed modeled residential UHF-EMF exposure from GSM antennas and ALS incidence from 2000–2012. The authors report a statistically significant exposure–response trend and higher ALS risk in the highest exposure category versus non-exposure in both…

Impact of extremely low-frequency electromagnetic field (100 Hz, 100 G) exposure on human glioblastoma U87 cells during Temozolomide administration.

Research RF Safe Research Library Jan 1, 2019

This in vitro study evaluated whether extremely low-frequency EMF exposure (100 Hz, 100 G) modifies the effects of temozolomide (100 µM) in human glioblastoma U87 cells over 120–144 hours. The authors report that combined treatment reduced stemness-associated markers (Nestin, CD133, Notch4) and increased GFAP…

Effects of 5-HT and 5-HT Receptor Agonists on Electromagnetic Field-Induced Analgesia in Rats.

Research RF Safe Research Library Jan 1, 2019

This animal study examined whether serotonergic signaling modifies analgesia associated with repeated ELF electromagnetic field exposure. Sixty-six male Wistar rats were exposed to 50 Hz, 5 mT for 2 hours/day over 15 days and then received 5-HT agonists or antagonists before analgesia testing. Agonists increased,…

Long-Term Study on the Effects of Housing C57BL/6NCrl Mice in Cages Equipped With Wireless Technology Generating Extremely Low-Intensity Electromagnetic Fields.

Research RF Safe Research Library Jan 1, 2019

This animal study characterized electromagnetic fields generated by digitally ventilated mouse cages with wireless monitoring technology and assessed clinicopathological outcomes over up to 1 year. DVC produced extremely low-intensity electric fields across a wide frequency range (5 Hz to 3 GHz). The authors report…

Correlation between the Lunar Phase and Tail-Lifting Behavior of Lizards () Exposed to an Extremely Low-Frequency Electromagnetic Field.

Research RF Safe Research Library Jan 1, 2019

This animal study examined long-term tail-lifting behavior in agamid lizards exposed to an ELF electromagnetic field (6 and 8 Hz; peak magnetic field 2.6 µT; peak electric field 10 V/m) versus controls, incorporating lunar phase and geomagnetic activity (K index) as explanatory variables. Regression analyses found…

Altered morphology and biochemistry of the female rat liver following 900 megahertz electromagnetic field exposure during mid to late adolescence.

Research RF Safe Research Library Jan 1, 2019

This animal study examined whether 900 MHz EMF exposure during mid to late adolescence affects the liver in female rats. Compared with control and sham groups, the exposed group showed occasional liver histopathological irregularities. The exposed group also had significantly decreased 8-OHdG and SOD levels, and the…

Treatment of Common Sunflower (Helianthus annus L.) Seeds with Radio-frequency Electromagnetic Field and Cold Plasma Induces Changes in Seed Phytohormone Balance, Seedling Development and Leaf Protein Expression.

Research RF Safe Research Library Jan 1, 2019

This study assessed pre-sowing sunflower seed treatments using vacuum, 5.28 MHz radio-frequency cold plasma, and an electromagnetic field for varying durations. The authors report faster germination with cold plasma (7 min) and EMF (15 min), while germination percentage was mostly unchanged except for a decrease…

Evaluation of the neuroprotective effects of electromagnetic fields and coenzyme Q on hippocampal injury in mouse.

Research RF Safe Research Library Jan 1, 2019

This animal study tested whether 50 Hz EMF exposure and/or CoQ10 could protect against TMT-induced hippocampal injury in mature female mice. CoQ10 and CoQ10+EMF were associated with improved spatial memory and reduced histological markers of cell death, alongside increased antiapoptotic markers. EMF alone reportedly…

The influence of electromagnetic fields generated by wireless connectivity systems on the occurrence of emotional disorders in women: A preliminary report.

Research RF Safe Research Library Jan 1, 2019

This preliminary cross-sectional study of 200 women working in healthcare and trade assessed associations between wireless-system EMF exposures and emotional disorders. The authors report that GSM 900/1800 base-station exposure contributed to depressive disorders among medical personnel, while WLAN exposure was…

Exposure to 50 Hz electromagnetic fields enhances hair follicle regrowth in C57BL/6 mice.

Research RF Safe Research Library Jan 1, 2019

This animal study in C57BL/6 mice reports that exposure to 50 Hz EMF affected hair follicle regrowth. It also reports increased proliferation of K15 stem cells in hair follicle regions. The authors interpret the findings as potentially beneficial for healing hair loss, but key methodological details are not provided…

Efficacy of pulsed electromagnetic fields and electromagnetic fields tuned to the ion cyclotron resonance frequency of Ca on chondrogenic differentiation.

Research RF Safe Research Library Jan 1, 2019

This in vitro study compared commonly used pulsed electromagnetic field (PEMF) exposures with electromagnetic fields tuned to satisfy the ion cyclotron resonance (ICR) condition for calcium. After 3 weeks, the calcium ICR condition was associated with increased glycosaminoglycans and type II collagen synthesis and…

Global gene expression changes reflecting pleiotropic effects of Irpex lacteus induced by low--intensity electromagnetic field.

Research RF Safe Research Library Jan 1, 2019

This laboratory study used RNA-seq to examine how low-intensity electromagnetic field (LI-EMF) exposure affects global gene expression in the fungus Irpex lacteus. Thousands of differentially expressed genes were reported immediately after exposure, with fewer changes after 3 h and 6 h recovery, and a subset of genes…

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