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The effects of short-term and long-term 2100 MHz radiofrequency radiation on adult rat auditory brainstem response

Research RF Safe Research Library Jan 1, 2025

This animal study examined 2100 MHz radiofrequency radiation exposure effects on auditory brainstem responses and brain oxidative/ultrastructural markers in adult rats. The 1-week exposure group showed prolonged ABR latencies and biochemical/structural changes consistent with oxidative stress and cellular injury. The…

Electromagnetic fields from mobile phones: A risk for maintaining energy homeostasis?

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses low-intensity RF-EMF exposure, primarily from mobile phones, with a focus on thermoregulation and energy homeostasis. It reports that many rodent studies at 900 MHz describe cold-like thermoregulatory and behavioral responses and molecular findings suggestive of WAT browning, while BAT…

5G-exposed human skin cells do not respond with altered gene expression and methylation profiles

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed human skin cells (fibroblasts and keratinocytes) to 5G-band electromagnetic fields for 2 hours and 48 hours using a fully blinded design. Exposures were up to ten times permissible limits, with sham exposure as a negative control and UV exposure as a positive control. The study reports…

Exploring the impact of environmental factors on male reproductive health through epigenetics

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses how environmental factors may affect male reproductive health through epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation. It reports that electromagnetic radiation, particularly from mobile phones and wireless…

An 1800 MHz Electromagnetic Field Affects Hormone Levels, Sperm Quality, and Behavior in Laboratory Rats

Research RF Safe Research Library Jan 1, 2025

This animal study exposed rats to a 1800 MHz electromagnetic field for 12 weeks and assessed hormones, sperm quality, and behavior. The abstract reports increased corticosterone, decreased thyroid-stimulating hormone, reduced sperm motility/viability, and increased anxiety-like behavior in exposed rats. Some hormonal…

A Mini-Review of the Potential Health Impacts of Indoor Radiation Exposure in Companion Animals

Research RF Safe Research Library Jan 1, 2025

This mini-review discusses indoor radiation sources that may affect companion animals, including radon, radionuclides in feed, radiofrequency sources (phones, Wi-Fi, pet tracking devices), solar radiation, and extremely low frequency radiation. It reports that indoor radiation may negatively impact companion animal…

Understanding Electromagnetic Hypersensitivity (EHS) From Mobile Phone Radiofrequency Radiation (RFR) Exposure: A Mixed-Method Study Protocol

Research RF Safe Research Library Jan 1, 2025

This paper presents a mixed-method study protocol examining electromagnetic hypersensitivity (EHS) in relation to mobile phone radiofrequency radiation exposure among undergraduate students. The quantitative component aims to identify predictors of EHS using a biopsychosocial model, while the qualitative component…

The effect on rat peripheral nerve morphology and function of a 900-MHz electromagnetic field applied in the prenatal period

Research RF Safe Research Library Jan 1, 2025

This animal study exposed pregnant Sprague Dawley rats to a 900 MHz electromagnetic field for 1 hour daily throughout gestation and assessed offspring outcomes postnatally. Sciatic nerve analyses at postnatal day 60 indicated persistent morphological alterations attributed to prenatal EMF exposure. However, the…

Effects of 700MHz radiofrequency radiation (5G lower band) on the reproductive parameters of female Wistar rats

Research RF Safe Research Library Jan 1, 2025

This animal study examined short- and long-term 700 MHz (lower-band 5G) radiofrequency exposure in female Wistar rats, comparing control, sham, and exposed groups. It reports no DNA damage and no change in estrous cycle length, but increased ovarian oxidative stress markers in exposed animals. Long-term exposure was…

The effects of radiofrequency radiation on male reproductive health and potential mechanisms (Review)

Research RF Safe Research Library Jan 1, 2025

This narrative review summarizes human and animal research on radiofrequency (RF) radiation exposure (e.g., mobile phones, Wi‑Fi, occupational sources) and male reproductive outcomes. It reports that the literature links RF exposure with reduced sperm quality and increased DNA damage, often alongside oxidative stress…

Use of Mobile and Cordless Phones and the Association with Prostate Cancer

Research RF Safe Research Library Jan 1, 2025

This pooled analysis of two prior human studies reports increased odds of prostate cancer associated with mobile phone use, with higher estimates for longer latency and higher cumulative hours. Cordless phone use is reported to show increased risk but not statistically significant overall, with one mid-range…

Repeated Head Exposures to a 5G-3.5 GHz Signal Do Not Alter Behavior but Modify Intracortical Gene Expression in Adult Male Mice

Research RF Safe Research Library Jan 1, 2025

This animal study examined repeated asymmetrical head exposure to a 5G-modulated 3.5 GHz signal in adult male mice for six weeks. It reports no significant changes in locomotion, anxiety, or object-based memory performance under the tested conditions. However, it found statistically significant but limited cortical…

The CB1R of mPFC is involved in anxiety-like behavior induced by 0.8/2.65 GHz dual-frequency electromagnetic radiation

Research RF Safe Research Library Jan 1, 2025

This animal study reports that dual-frequency RF EMR exposure (0.8/2.65 GHz, 4 W/kg) induced anxiety-like behavior in mice. It also reports reduced CB1R and endocannabinoid levels in the mPFC and altered endocannabinoid system markers in the BLA. CB1R overexpression or knockdown in the mPFC reportedly decreased or…

Melatonin and omega-3 neuroprotection in prenatal rat spinal cord exposed to 900 MHz electromagnetic field.

Research RF Safe Research Library Jan 1, 2025

This animal study examined prenatal 900 MHz EMF exposure (2 hours/day for 21 days) in pregnant rats and assessed spinal cord outcomes in male offspring at postnatal day 35. Volume-based stereological measures (GM/WM ratios and total spinal cord volume) did not differ significantly between groups. Microscopy reported…

Prophylactic Effects of Radiofrequency Electromagnetic Field on Pulmonary Ischemia-Reperfusion via HIF-1α/eNOS Pathway and BCL2/BAX Signaling.

Research RF Safe Research Library Jan 1, 2025

This animal study tested whether RF-EMF exposure modifies lung ischemia-reperfusion injury in male Wistar rats. IR increased histologic injury, inflammatory/apoptotic markers, oxidative stress indices, and Hif-1α/eNOS/BAX while decreasing BCL2. The IR + RF-EMF group reportedly improved across measured parameters, and…

Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review

Research RF Safe Research Library Jan 1, 2025

This systematic review evaluated RF-EMF exposure and cancer outcomes in experimental animals, including 52 studies (20 chronic cancer bioassays), using narrative synthesis due to substantial heterogeneity. The review reports no or minimal evidence of RF-EMF-related cancer outcomes for many organ systems, but reports…

The effects of radiofrequency exposure on male fertility: A systematic review of human observational studies with dose-response meta-analysis (SR 3)

Research RF Safe Research Library Jan 1, 2024

This systematic review and dose-response meta-analysis synthesizes human observational studies on radiofrequency EMF exposure and male fertility outcomes. It reports evidence of an association between RF exposure and poorer sperm parameters, including reduced quality, motility, and viability. The authors frame the…

Effects of radiofrequency field from 5G communication on fecal microbiome and metabolome profiles in mice

Research RF Safe Research Library Jan 1, 2024

This animal study exposed adult male C57BL/6 mice to a 4.9 GHz radiofrequency field for three weeks (1 hour/day) and compared them with a sham group. The abstract reports altered fecal microbiome composition with reduced diversity in the RF group, along with 258 significantly differentially abundant fecal…

Effects of Head-Only Exposure to 900 MHz GSM Electromagnetic Fields in Rats: Changes in Neuronal Activity as Revealed by c-Fos Imaging without Concomitant Cognitive Impairments.

Research RF Safe Research Library Jan 1, 2024

This rat study used a head-only 900 MHz GSM exposure system to assess brain activity changes via c-Fos imaging and to test spatial memory performance. Acute exposure (2 h) was associated with dose-dependent, region-specific increases in c-Fos expression, while repeated pre-training exposures were associated with…

Comparison of a radiofrequency electric and magnetic field source-based job-exposure matrix with personal radiofrequency exposure measurements.

Research RF Safe Research Library Jan 1, 2024

This study compared historical occupational RF-EMF exposure estimates from the INTEROCC RF job-exposure matrix (RF-JEM) with recent personal RF-EMF measurements from the OccRF-Health study in two countries. Agreement between the two approaches was poor for both exposure prevalence and 8-hour time-weighted average…

Exposure to Radiofrequency Induces Synaptic Dysfunction in Cortical Neurons Causing Learning and Memory Alteration in Early Postnatal Mice.

Research RF Safe Research Library Jan 1, 2024

This animal study examined 1850 MHz RF-EMF exposure (SAR 4.0 W/kg) in early postnatal mice and assessed synaptic and behavioral outcomes. The abstract reports reductions in dendritic spine maturation markers, decreases in PSD-95 puncta, inhibited neurite outgrowth, and downregulation of synapse-related genes in…

Anthropogenic electromagnetic radiation alters the transcription levels of the genes encoding the SIFamide and myoinhibitory peptide and their receptors in Ixodes ricinus synganglion.

Research RF Safe Research Library Jan 1, 2024

This animal study used qRT-PCR to assess whether 900 MHz radiofrequency electromagnetic field exposure alters neuropeptide-related gene transcription in Ixodes ricinus synganglia. The abstract reports that 40 V/m exposure for at least 60 minutes significantly suppressed transcript levels of sifa, mip, and their…

Personal exposure to radiofrequency electromagnetic fields in various occupations in Spain and France.

Research RF Safe Research Library Jan 1, 2023

This study conducted personal full-shift RF-EMF measurements in 333 workers across 46 occupations in Spain and France. Most 1-second measurements of electric and magnetic fields were below the device detection limit (≥1% of 1998 ICNIRP standards), though many workers had at least one detectable reading. A small…

Low-energy amplitude-modulated radiofrequency electromagnetic fields as a systemic treatment for cancer: Review and proposed mechanisms of action

Research RF Safe Research Library Sep 8, 2022

This review discusses low-energy amplitude-modulated RF EMF (27.12 MHz carrier with low Hz–kHz envelope modulation) delivered systemically via intrabuccal antenna devices as a potential treatment for advanced hepatocellular carcinoma. It reports preclinical inhibition of cancer growth in vitro and in mouse xenograft…

The effect of long-term radiofrequency exposure on cognition in human observational studies: A protocol for a systematic review.

Research RF Safe Research Library Jan 1, 2022

This paper presents a protocol for a systematic review of human observational studies assessing long-term radiofrequency (100 kHz to 300 GHz) EMF exposure and cognitive outcomes. It plans to include cohort and case-control studies with at least 6 months follow-up and validated cognitive measures, and to evaluate…

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