Archive

This review synthesizes evidence on how direct current and alternating current electrical stimulation affect neurons and glia in the central nervous system, spanning basic research and clinical translation. It reports polarity- and parameter-dependent effects on axonal growth, along with immunomodulatory glial…

This prospective study enrolled 10 adults with atraumatic or traumatic brain injury who received tailored cranial EMF stimulation using a portable helmet with real-time EMF measurement and parameter adjustment. The abstract reports symptom resolution or remaining asymptomatic in 8 participants at varying stimulation…

This animal validation study tested a Mu-metal-shielded helmet system with proprietary induction sensor stimulators for non-invasive recording and stimulation of neural electromagnetic activity through porcine skulls. The authors report that EMFs penetrated the swine skull and that sensor performance remained…

This prospective clinical study measured brain electromagnetic field (EMF) patterns in 10 adult patients with traumatic or atraumatic brain injury using a noninvasive 20-sensor helmet within 24 hours of presentation. Using FFT-based analysis, the authors report several targeted frequencies of interest between 5.2 and…

This animal feasibility study evaluated whether real-time measured, targeted sinusoidal EMF stimulation could normalize traumatic brain injury (TBI)-related changes in neuronally generated EMF patterns. In one Yucatan miniswine with controlled cortical impact, AI modeling distinguished pre-injury, post-injury, and…

This computational study used finite element modeling to estimate the electric field distribution in the brain during tDCS for two electrode montages targeting the left DLPFC. It systematically varied isotropic tissue conductivity profiles to assess sensitivity of predicted E-field magnitude and components in the…

This in vitro study examined how cortical neuron morphology and cell type relate to responses under subthreshold and suprathreshold uniform electric fields in rat motor cortex slices. The authors report that morphology correlates with subthreshold somatic polarization and that layer V pyramidal neurons are predicted…