Archive

This in vitro and rat study evaluated sinusoidal electromagnetic field (EMF) treatment of bone marrow mesenchymal stem cells (BMSCs) seeded on 3D-printed scaffolds for repairing critical-sized calvarial defects. The authors report that EMF-treated cell scaffolds accelerated bone defect repair in rats.…

This in vitro and rat-model study evaluated sinusoidal low-frequency EMF combined with a PCL/nHA scaffold seeded with BMSCs for intervertebral fusion. The authors report enhanced osteogenic differentiation of BMSCs and pro-osteogenic effects of conditioned medium from EMF-treated BMSCs, with suggested involvement of…

This in vitro and animal study evaluated whether extremely low frequency EMF exposure (1 mT, 45 Hz, 8 h/day) combined with Fe-based nanomagnetic particles enhances osteogenesis. The authors report no detectable cytotoxicity and increased osteogenic markers/proteins with combined NMP + EMF exposure, alongside…

This paper presents an in vitro, noncontact solenoid-coil device designed to deliver intermediate-frequency induced electromagnetic fields that generate electric fields in cell and tissue cultures. The system aims to improve field characterization and reduce conductive heating compared with electrode-based approaches…

This animal and in vitro study evaluated electromagnetic fields (EMF) treatment combined with a 3D-printed PLA/HA scaffold seeded with rat bone marrow mesenchymal stem cells (BMSCs) for cranial defect repair. The authors report that EMF enhanced BMSC proliferation and osteogenic differentiation and was partly…

This in vitro study fabricated PCL nanofibrous scaffolds containing cobalt-zinc ferrite nanoparticles and evaluated physicochemical/mechanical properties and cell-related outcomes. The abstract reports improved hydrophilicity, biodegradation, and stress at break with CZF-NP incorporation, and improved L929 cell…

This in vitro study reports that a single pulsed electromagnetic field (0.2 Hz) increased expression of tenogenic genes and reduced expression of a matrix-degradation/inflammatory gene (Mmp1) in tendon cells. After 5 days of exposure (3 min/day), collagen type I and total collagen synthesis protein levels were…

This animal and in vitro study evaluated sinusoidal electromagnetic field (SEMF) exposure combined with VEGF in rat mesenchymal stem cells and in a rat cranial defect model using rBMSC-laden PCL/HA scaffolds. The authors report increased osteogenic and endothelial marker expression with SEMF and VEGF, with a slight…

This in vitro study compared commonly used pulsed electromagnetic field (PEMF) exposures with electromagnetic fields tuned to satisfy the ion cyclotron resonance (ICR) condition for calcium. After 3 weeks, the calcium ICR condition was associated with increased glycosaminoglycans and type II collagen synthesis and…

This animal study examined whether electromagnetic field (EMF) pretreatment has lasting (“legacy”) effects on rat bone marrow mesenchymal stem cells (BMSCs) and whether EMF-pretreated BMSC sheets improve fracture nonunion healing in rats. The authors report increased BMSC proliferation and enhanced…

This study reports synthesizing hydroxyapatite and carbonate-substituted hydroxyapatite using ultrasound and microwave radiation as processing methods. The authors report that these physical factors produced calcium-deficient hydroxyapatite and B-type carbonated apatite and increased in vitro bioactivity compared…

This in vitro study exposed human osteoarthritic and non-osteoarthritic chondrocyte pellets to a sinusoidal 15 Hz electromagnetic field at 5 mT or 8 mT for 7 days. Under 5 mT, osteoarthritic chondrocytes showed increased expression of cartilage-related genes (COL2A1 and ACAN) compared with controls, while…

This in vitro materials study compares microwave irradiation versus conventional water-bath heating for synthesizing HPMC-graft-(PVA-co-acrylic acid) hydrogels loaded with captopril. The authors report that microwave-synthesized hydrogels had more uniformly porous structures and higher swelling ratios, with…

This animal and in vitro study reports a method to lyse tumor cells mechanically using targeted superparamagnetic iron oxide nanoparticles rotated by a weak alternating magnetic field. Nude mice with head and neck tumors received cetuximab-coated nanoparticles and 4 Hz field exposures for 30 minutes on alternating…

This in vitro study examined how different external magnetic field conditions affect isoniazid release from superparamagnetic iron oxide microspheres. The abstract reports that magnetic fields accelerated drug release, with faster release in acidic (pH 3) conditions and the fastest completion (2 hours) under an…

This in-vitro study examined whether 50 Hz extremely low frequency electromagnetic fields affect proliferation in HeLa and CHO cell cultures. The abstract reports increased proliferation in exposed cells versus controls, with the largest reported increase under repetitive exposure at 2.49 mT (40 minutes every 12…

This in vitro study tested whether a static magnetic field (SMF) could enhance the effects of cisplatin or adriamycin in Hepa1-6 tumor cells. The abstract reports that SMF combined with either drug increased growth inhibition and was associated with cell-cycle arrest, increased DNA damage, and more severe membrane…

This in vitro experimental study examined how an AC electric field influences actin filament (F-actin) movement on a myosin-coated substrate. The authors report that the field induces electro-orientation torque that aligns movement perpendicular toward electrode edges, with alignment increasing with field strength.…