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Use of non-ionizing electromagnetic fields for the treatment of cancer

Research RF Safe Research Library Jan 1, 2018

This review discusses the limited options for certain cancers and introduces non-ionizing electromagnetic fields as an emerging concept for cancer treatment. It summarizes the history of EMF use in medicine from the 1890s and describes novel methods aimed at targeting and treating cancer with non-ionizing radiation.…

Effects of radiofrequency radiation in the presence of gold nanoparticles for the treatment of renal cell carcinoma.

Research RF Safe Research Library Jan 1, 2017

This in vitro study evaluated radiofrequency (RF) radiation with and without gold nanoparticles in human embryonic kidney (HEK) cancer cells as a potential approach for renal cell carcinoma treatment. The authors report reduced cell survival in one RF-exposed group versus control, and additional reductions in…

Different profiles of the mRNA levels of DNA repair genes in MCF-7 and SH-SY5Y cells after treatment with combination of cisplatin, 50-Hz electromagnetic field and bleomycin.

Research RF Safe Research Library Jan 1, 2017

This in vitro study examined whether a 50-Hz, 0.50 mT intermittent electromagnetic field modifies responses to cisplatin and bleomycin in MCF-7 and SH-SY5Y cells. The authors report increased susceptibility in MCF-7 cells with EMF added to cisplatin+bleomycin, while SH-SY5Y susceptibility was unchanged. They also…

Comments on "Radiofrequency electromagnetic fields and some cancers of unknown etiology: An ecological study".

Research RF Safe Research Library Jan 1, 2017

This correspondence discusses a prior ecological study examining a possible association between RF-EMF exposure in Albacete, Spain and cancer incidence. The cancers mentioned include lymphomas and brain tumors. The correspondence indicates that shortcomings of the ecological study are discussed, but does not detail…

Cytotoxicity of temozolomide on human glioblastoma cells is enhanced by the concomitant exposure to an extremely low-frequency electromagnetic field (100Hz, 100G).

Research RF Safe Research Library Jan 1, 2017

This in vitro study tested whether an extremely low-frequency EMF (100 Hz, 100 G) could enhance temozolomide cytotoxicity in human glioma cell lines (U87 and T98G). The authors report that combined EMF and temozolomide increased apoptosis relative to either treatment alone and was accompanied by changes in…

Radiofrequency electromagnetic fields and some cancers of unknown etiology: An ecological study.

Research RF Safe Research Library Jan 1, 2017

This preliminary ecological study examined whether RF-EMF exposure in Albacete (Spain) correlated with incidence of lymphomas and brain tumors from January 2012 to May 2015. Personal RF-EMF exposure was measured across 14 frequency bands using an EME Spy 140 exposimeter and compared with tumor incidence by…

Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.

Research RF Safe Research Library Jan 1, 2017

This study reports a technology that records a specific radiofrequency electromagnetic energy signal associated with EGFR siRNA and applies it to cells. The abstract describes reductions in EGFR mRNA and protein expression versus controls, with specificity assessed using RNA microarray and antibody dot blot array. It…

Quantum mechanical model for the anticarcinogenic effect of extremely-low-frequency electromagnetic fields on early chemical hepatocarcinogenesis.

Research RF Safe Research Library Jan 1, 2017

This study develops a quantum-mechanical radical pair mechanism model to examine how an extremely-low-frequency electromagnetic field (ELF-EMF) might influence early chemical hepatocarcinogenesis in rats. The model evaluates singlet-state recombination and quantum yield under a low magnetic field effect, proposing…

Decreased survival of glioma patients with astrocytoma grade IV (glioblastoma multiforme) associated with long-term use of mobile and cordless phones

Research RF Safe Research Library Oct 16, 2014

This analysis examined survival among 1678 glioma patients from two case-control study periods (1997–2003 and 2007–2009) in relation to wireless phone use. In the >20 years latency group, the authors report increased hazard ratios for glioma overall and for astrocytoma grade IV (glioblastoma multiforme), with hazard…

Exposure to radio-frequency electromagnetic fields from broadcast transmitters and risk of childhood cancer: a census-based cohort study

Research RF Safe Research Library Apr 1, 2014

This census-based cohort study in Switzerland examined modeled RF-EMF exposure from broadcast transmitters and childhood cancer risk using two cohort approaches. Across analyses, no association was reported for all cancers or childhood leukemia. Findings for CNS tumors were inconsistent, and the incidence density…

Distance from residence to power line and risk of childhood leukemia: a population-based case-control study in Denmark

Research RF Safe Research Library Jan 1, 2014

This population-based case-control study in Denmark examined whether distance from residence at birth to high-voltage overhead power lines was associated with childhood leukemia. Using GIS-based distance measures, the study did not find higher leukemia risk for children living within 0–199 m or 200–599 m of 132–400…

Autophagy and enhanced chemosensitivity in experimental pancreatic cancers induced by noninvasive radiofrequency field treatment.

Research RF Safe Research Library Jan 1, 2014

This study tested noninvasive 13.56 MHz radiofrequency electric fields as a treatment adjunct for pancreatic ductal adenocarcinoma in cell lines and mouse xenograft models. The authors report RF exposure caused cytotoxicity in PDAC cells via autophagy (not apoptosis) and that normal pancreatic ductal epithelial cells…

Optimization of a therapeutic electromagnetic field (EMF) to retard breast cancer tumor growth and vascularity.

Research RF Safe Research Library Jan 1, 2014

This animal study evaluated a therapeutic 120 Hz pulsed EMF device (10–20 mT) in C3H mice bearing implanted murine mammary adenocarcinoma tumors. Across seven treated groups, EMF exposure over 12 days was reported to suppress tumor growth, with specific dose/time regimens described as most effective. The authors also…

Multifocal Breast Cancer in Young Women with Prolonged Contact between Their Breasts and Their Cellular Phones

Research RF Safe Research Library Jan 1, 2013

This 2013 case series describes four young women (ages 21–39) with multifocal invasive breast cancer who reportedly carried smartphones directly against their breasts in their brassieres for prolonged periods over several years. Tumors were reported to occur in areas immediately underlying phone contact, with imaging…

Effect of magnetic fields on tumor growth and viability.

Research RF Safe Research Library Jan 1, 2011

This animal study evaluated whether magnetic field exposure affects breast tumor growth and viability in mice injected with breast cancer cells. Tumor growth was monitored in real time using luciferase labeling and an in vivo imaging system. The authors report that 360 minutes of daily magnetic field exposure for up…

Electric field analysis of breast tumor cells.

Research RF Safe Research Library Jan 1, 2011

This paper reports a MAXWELL 3D simulation study of electric field distribution in a tissue/tumor model relevant to electrical-pulse-mediated drug delivery. The authors report lower electric field strength in tumor tissue compared with normal cells. They interpret this as potentially increasing tumor susceptibility…

Cell phones and brain tumors: a review including the long-term epidemiologic data

Research RF Safe Research Library Jan 1, 2009

This paper presents a meta-analysis of 11 peer-reviewed epidemiologic studies examining long-term (>=10 years) cell phone use with laterality analyses. It reports that long-term use is associated with an approximately doubled risk of an ipsilateral brain tumor. The abstract states statistical significance for glioma…

Noninvasive radiofrequency field-induced hyperthermic cytotoxicity in human cancer cells using cetuximab-targeted gold nanoparticles.

Research RF Safe Research Library Jan 1, 2008

This in vitro study reports that shortwave (MHz-range) RF exposure can induce strong cytotoxicity in EGFR-overexpressing human cancer cells when those cells have internalized cetuximab-targeted gold nanoparticles. Control nanoparticles showed minimal uptake and substantially lower cytotoxicity under RF exposure. An…

Mobile phone use and cancer

Research RF Safe Research Library Jan 1, 2004

This narrative review discusses potential public health consequences of widespread mobile phone use and the controversy around long-term cancer risks. It states that evidence from epidemiological and experimental studies suggests long-term exposure to mobile phone emissions may be linked to a small to moderate…

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