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Occupational exposure to extremely low-frequency magnetic fields (ELF-MF) and postmenopausal breast cancer risk

Research RF Safe Research Library Jan 1, 2025

This population-based case-control study in Montréal (2008–2011) evaluated occupational extremely low-frequency magnetic field (ELF-MF) exposure and postmenopausal breast cancer risk using a job-exposure matrix linked to lifetime job histories. Overall, it reports no association between occupational ELF-MF exposure…

Effect of electromagnetic radiations from mobile towers on genetic damage and genetic polymorphism in humans: a review on India's perspective

Research RF Safe Research Library Jan 1, 2025

This narrative review examines research on radiofrequency electromagnetic radiation (RF-EMR) from mobile towers and its potential association with genetic damage and genetic polymorphism in humans, with an emphasis on India. The abstract states that RF-EMR exposure may affect genetic material and suggests a link…

Systematic reviews and meta-analyses for the WHO assessment of health effects of exposure to radiofrequency electromagnetic fields, an introduction

Research RF Safe Research Library Jan 1, 2025

This editorial introduces a special issue supporting the WHO assessment of health effects from RF-EMF exposure, based on nine protocols and twelve systematic reviews developed over four years by more than 80 experts. It summarizes that human evidence for major cancers was moderate-certainty for no or only small…

Carcinogenicity of Radio-Frequency Radiation: Similarities and Differences Between Outcomes of Two Studies

Research RF Safe Research Library Jan 1, 2025

This review compares two epidemiologic studies of radio-frequency radiation (RFR) exposure among military personnel with overlapping patient groups. One study reported a statistically significant increase in cancer among exposed individuals, while the other did not, which the review attributes to a smaller sample…

Trends in Malignant and Benign Brain Tumor Incidence and Mobile Phone Use in the U.S. (2000-2021): A SEER-Based Study

Research RF Safe Research Library Jan 1, 2025

This SEER-based ecological study examined U.S. trends (2000–2021) in malignant and benign brain tumor incidence and compared them with national mobile phone subscription trends. Malignant brain tumor incidence in adolescents and adults declined slightly, while benign brain tumor incidence increased over time;…

The proliferation rates of HT-1080 human fibrosarcoma cells can be accelerated or inhibited by weak static and extremely low frequency magnetic fields

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed HT-1080 human fibrosarcoma cells for 4 days to weak extremely low frequency magnetic fields (10 μT, 12–33 Hz) superimposed on a 45 μT static field. The authors report frequency- and amplitude-dependent increases or decreases in cell growth, including sharp inversions near 16.5 Hz with…

A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields

Research RF Safe Research Library Jan 1, 2025

This narrative review discusses biological mechanisms and reported health effects of anthropogenic extremely low frequency (ELF) and wireless communication (WC) electromagnetic fields. It highlights oxidative stress and DNA damage as key mechanistic endpoints and proposes an IFO-VGIC pathway linking EMF exposure to…

Carcinogenicity of extremely low-frequency magnetic fields: A systematic review of animal studies

Research RF Safe Research Library Jan 1, 2025

This PRISMA-based systematic review evaluated 54 animal studies on the carcinogenicity of extremely low-frequency (ELF) magnetic fields. The authors report very little evidence that ELF magnetic fields alone are carcinogenic. Findings on co-carcinogenicity (ELF MFs combined with other agents) are inconclusive, and…

Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review

Research RF Safe Research Library Jan 1, 2025

This systematic review evaluated RF EMF exposure and cancer outcomes in experimental animals, including chronic cancer bioassays and tumor-promotion designs. Across 52 included studies, the authors report high certainty of evidence for increased malignant heart schwannomas and gliomas in male rats, and moderate…

Residential exposure to magnetic field due to high-voltage power lines and childhood leukemia risk in mainland France - GEOCAP case-control study

Research RF Safe Research Library Jan 1, 2025

This French GEOCAP registry-based case-control study evaluated childhood acute leukemia risk in relation to residential proximity to high-voltage overhead power lines and modeled ELF magnetic-field exposure. It reports an increased risk for children under 5 living within 50 m of power lines, particularly when…

Use of Mobile and Cordless Phones and the Association with Prostate Cancer

Research RF Safe Research Library Jan 1, 2025

This pooled analysis of two prior human studies reports increased odds of prostate cancer associated with mobile phone use, with higher estimates for longer latency and higher cumulative hours. Cordless phone use is reported to show increased risk but not statistically significant overall, with one mid-range…

Magneto-oncology: a radical pair primer

Research RF Safe Research Library Jan 1, 2025

This mini-review discusses the radical pair mechanism as a plausible biophysical route by which external magnetic fields could influence biochemical processes in living systems. It is intended as a primer for magneto-oncology researchers to assess whether observed magnetic-field-related biomedical effects may be…

Enhanced Antiproliferative Activity of Docetaxel by Extremely Low Frequency Electromagnetic Fields in MCF-7 Breast Cancer Cells.

Research RF Safe Research Library Jan 1, 2025

This in vitro study tested whether extremely low-frequency electromagnetic fields (50 Hz, 20 mT) enhance docetaxel effects in MCF-7 breast cancer cells. The authors report that combining ELF-EMF with docetaxel produced a similar reduction in cell viability at a lower docetaxel concentration than docetaxel alone,…

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields.

Research RF Safe Research Library Jan 1, 2025

This study reports that glioblastoma-specific amplitude-modulated 27.12 MHz RF electromagnetic fields (delivered intrabuccally) inhibited proliferation in several glioblastoma cell lines exposed 3 hours/day at patient-matched levels. The authors propose a mechanism involving CACNA1H and modulation of the “Mitotic…

Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review

Research RF Safe Research Library Jan 1, 2025

This systematic review evaluated RF-EMF exposure and cancer outcomes in experimental animals, including 52 studies (20 chronic cancer bioassays), using narrative synthesis due to substantial heterogeneity. The review reports no or minimal evidence of RF-EMF-related cancer outcomes for many organ systems, but reports…

Is Cellphone Carrying Below the Waist (Exposure to Non-Ionizing Radiation) Contributing to the Rapid Rise in Early-Onset Colorectal Cancer?

Research RF Safe Research Library Jan 1, 2024

This conference abstract reports a pilot matched case-control study examining whether carrying a cellphone below the waist is associated with early-onset colorectal cancer (EOCRC). The authors report higher EOCRC likelihood among those who carried phones below the waist, with the strongest association for ipsilateral…

The Systematic Review on RF-EMF Exposure and Cancer by Karipidis et al. (2024) has Serious Flaws that Undermine the Validity of the Study's Conclusions

Research RF Safe Research Library Jan 1, 2024

This letter critiques the WHO-sponsored systematic review by Karipidis et al. (2024) on RF-EMF exposure and cancer risk. The authors argue the review has serious methodological and interpretative flaws, including issues with study selection and data analysis. They contend that the review’s conclusion of "no clear…

Relationship between radiofrequency-electromagnetic radiation from cellular phones and brain tumor: meta-analyses using various proxies for RF-EMR exposure-outcome assessment

Research RF Safe Research Library Jan 1, 2024

Moon et al. (2024) report a systematic review and meta-analysis on cellular phone RF-EMR and brain tumor risk. The abstract summary states elevated risks for three brain tumor types in analyses considering ipsilateral (same-side) phone use and reports increased risk with heavy and long-term use. The text also…

External low energy electromagnetic fields affect heart dynamics: surrogate for system synchronization, chaos control and cancer patient's health.

Research RF Safe Research Library Jan 1, 2024

This paper discusses how low-energy, specifically modulated electromagnetic fields delivered via an active closed-loop medical device may temporarily alter plasma membrane ionic flow and heart oscillation dynamics. It frames heart rate dynamics as a surrogate for systemic synchronization/entrainment and suggests…

Electromagnetic field as a possible inhibitor of tumor invasion by declining E-cadherin/N-cadherin switching in triple negative breast cancer.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed breast cell lines to a 1 Hz, 100 mT ELF-EMF for 5 days (2 h/day) and assessed migration, invasion, and cadherin expression. The authors report reduced migration and invasion in MDA-MB231 cells versus sham exposure. They also report increased E-cadherin and decreased N-cadherin in MDA-MB231…

The exposure to extremely low frequency electromagnetic-fields inhibits the growth and potentiates the sensitivity to chemotherapy of bidimensional and tridimensional human osteosarcoma models.

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested a specific extremely low frequency electromagnetic field (ELF-EMF) on three human osteosarcoma cell lines grown in 2D and 3D spheroid models. The abstract reports that ELF-EMF exposure inhibited proliferation and altered mitochondrial metabolism in the cancer models. It also reports…

Induction of apoptosis in B16-BL6 melanoma cells following exposure to electromagnetic fields modeled after intercellular calcium waves.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed B16-BL6 melanoma cells to a time-varying EMF modeled after intercellular calcium-wave firing patterns. The abstract reports a 50.3% reduction in viable cells after a single 40-minute exposure and microscopy findings consistent with apoptosis and nuclear fragmentation versus control. The…

Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells

Research RF Safe Research Library Nov 7, 2023

This in vitro study characterized spinning oscillating magnetic field (sOMF) stimulation patterns that the authors report can induce cytotoxicity in two types of human glioma cells. The reported effect was linked to a critical rise in superoxide, and was reversed by the antioxidant Trolox, suggesting ROS involvement.…

Effects of 2.4 GHz radiofrequency electromagnetic field (RF-EMF) on glioblastoma cells (U -118 MG).

Research RF Safe Research Library Jan 1, 2023

This in vitro study exposed glioblastoma (U-118 MG) and human embryonic kidney (Hek-293) cells to 2.4 GHz RF-EMF for 24–72 hours, with or without a dielectric screen. The authors report a significant decrease in cell viability after exposure in both cell lines. The decrease was described as greater in glioblastoma…

P53 status, and G2/M cell cycle arrest, are determining factors in cell-death induction mediated by ELF-EMF in glioblastoma.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested ELF-EMF exposure in U87 and U251 glioblastoma cell lines and assessed apoptosis, cell-cycle distribution, cell size, and mRNA expression of cell-cycle genes. The authors report higher apoptosis induction and increased G2/M arrest in U87 compared with U251, alongside increased U87 cell size…

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