Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca Influx in Osteoprogenitor Cells.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study compared continuous versus intermittent 16 Hz ELF-PEMF exposure strategies in osteoprogenitor (SCP-1) cells. Intermittent exposure (10 min every 8 h) was reported to enhance cell numbers and osteogenic function relative to continuous daily exposure (30 min every 24 h). The authors report increased…
Electromagnetic field treatment increases purinergic receptor P2X7 expression and activates its downstream Akt/GSK3β/β-catenin axis in mesenchymal stem cells under osteogenic induction.
Research
RF Safe Research Library
Jan 1, 2019
This study examined how electromagnetic field (EMF) treatment influences osteogenic differentiation mechanisms in human bone marrow mesenchymal stem cells and tested a combined therapy in an ovariectomized rat osteoporosis model. The authors report that EMF exposure increased P2X7 receptor expression during…
Effects of electromagnetic fields on bone loss in hyperthyroidism rat model.
Research
RF Safe Research Library
Jan 1, 2017
This animal study evaluated whether extremely low frequency EMF exposure affects bone loss in a levothyroxine-induced hyperthyroidism rat model. Rats exposed to 15 Hz/1 mT EMF plus levothyroxine showed improved bone mineral density, mechanical measures, and partially restored trabecular bone architecture compared…
[Effects of static magnetic field at different times on the proliferation and differentiation of osteoblasts in vitro].
Research
RF Safe Research Library
Jan 1, 2012
This in vitro study exposed newborn rat calvarial osteoblasts to a 3.9 mT static magnetic field for varying durations (0–4 hours). The authors report increased cell proliferation and markers of osteoblast differentiation and mineralization versus control, including higher ALP activity, calcium content, and…
[Time effect of sinusoidal electromagnetic field on enhancing the maturation and mineralization of osteoblasts in vitro].
Research
RF Safe Research Library
Jan 1, 2011
This in vitro study exposed newborn rat calvarial osteoblasts to 50 Hz sinusoidal electromagnetic fields at 1.8 mT for different daily exposure times (0.5–3.0 h). The authors report inhibited osteoblast proliferation at longer exposure times, alongside increased differentiation markers (ALP activity) and…