{"id":"HHS-OASH-2026-0397-5670","number":"5670","name":"C Peck","organization":"","posted":"2026-10-27T04:00Z","received":"2026-10-21T04:00Z","body":"•\tWireless radiation disrupts lymphocytes by opening calcium channels (VGCC's) in cell membrane and increasing intraceullar Ca2+ (Puri et al, 2019, attached), thereby assisting bacterial and viral infections.  \n•\tCell phone radiation impairs DNA repair in lymphocytes https://onlinelibrary.wiley.com/doi/abs/1\n•\tAfter 30 days of exposure time, 1 h/day EMF exposure resulted in significant decrease in immunoglobulin levels (IgA, IgE, IgM, and IgG); total leukocyte, lymphocyte, eosinophil and basophil counts; and a significant increase in neutrophil and monocyte counts. These changes were more increased in the group exposed to 2 h/day EMF. Vitamin D supplementation in EMF-exposed rats reversed these results when compared with EMF-exposed groups. In contrast, 7, 14, and 21 days of EMF exposure produced nonsignificant differences in these parameters among all experimental groups. We concluded that exposure to mobile phone radiation compromises the immune system of rats, and vitamin D appears to have a protective effect.  https://pubmed.ncbi.nlm.nih.gov/27901344/ \n•\tGSM cell phone radiation microwaves under specific conditions of exposure affected human lymphocytes similar to stress response https://www.researchgate.net/publication/3165836_Nonthermal_GSM_Microwaves_Affect_Chromatin_Conformation_in_Human_Lymphocytes_Similar_to_Heat_Shock\n•\tAs compared to the control group in the radar operators a statistically significant decrease in the total T8 cell count and a significant increase in the IgM level was found pointing to the radiation induced disorders in lymphocyte system. https://pubmed.ncbi.nlm.nih.gov/2131394/\nRead more on effects of wireless radiation and 5G on the immune system https://mdsafetech.org/immune-system/ \nStudies that shows that wireless radiation affects vitamin D and glutathione:\n•\tMarshall 2016 reported wireless radiation lowers vitamin D receptor (VDR) activity by changing the shape of the VDR, thus impairing VDR activity and its ability to bind with vitamin D, and that this effect peaks at just under 6 GHz https://www.researchgate.net/profile/Trevor_Marshall2/publication/305254443_Electrosmog_and_autoimmune_disease/links/5785e9a008ae3949cf546f52.pdf?origin=publication_detail  (Wi-Fi uses 2.45 and 5 GHz, but just recently, WiFi using 6 GHz was introduced in 2020 https://blogs.cisco.com/networking/wi-fis-new-6ghz-spectrum-is-a-new-frontier)  \n•\tBelpomme et al, 2015 reported vitamin D deficiency can result from inflammation caused by chronic wireless radiation exposure  http://www.ehs-mcs.org/fichiers/1454070991_Reliable_biomarkers.pdf   \n•\tGaraj-Vrhovac  et. al, 2011 found that radar workers, after 10 years, had glutathione that was more than 50% lower than non-radar workers.   “The glutathione concentration in the exposed group was significantly lower than in controls (1.24 vs. 0.53) whereas the concentration of malondialdehyde was significantly higher (1.74 vs. 3.17), indicating oxidative stress. Results suggests that pulsed microwaves from working environment can be the cause of genetic and cell alterations and that oxidative stress can be one of the possible mechanisms of DNA and cell damage.”  Results were statistically significant (p<0.05).  Average exposure levels for radar workers were no higher than 0.00000835 W/kg, or 8.35 E-6 W/kg, well below government exposure standards  (FCC Whole Body SAR limit is 0.08W/kg average.)  http://www.sciencedirect.com/science/article/pii/S1438463910001069 (my highlighted copy attached)\n•\tDeluca et al, 2014.  https://www.hindawi.com/journals/mi/2014/924184/ found reduced levels of glutathione and impaired detoxification ability in those with microwave sickness (EHS).  Risk of EHS development was increased 9.7 times in individuals who are missing two genes GSTM1 and GSTT1, which are glutathione S-transferase (GST) enzymes that detoxify by conjugation with glutathione  \no\ta statistically significant lowered level of antioxidant/detoxification enzymatic activity of GST (glutathione S-transferase) in EHS compared to non-EHS (~1.9 in EHS vs. ~2.5 in non-EHS, p=0.000001, see Figure 5a) \no\ta statistically significant increased level of antioxidant/detoxification enzymatic activity of GPX (glutathione peroxidase) in EHS compared to non-EHS (~24.9 in EHS vs. ~22.8 in non-EHS, p=0.012151, see Figure 5b)\n\n\n","attachments":["https://downloads.regulations.gov/HHS-OASH-2026-0397-5670/attachment_1.pdf"],"attachment_inventory":true,"withheld":false,"source":"https://www.regulations.gov/comment/HHS-OASH-2026-0397-5670","tags":["health-experiences","sleep-cognition","biology-metabolism","exposure-places","policy-standards","research-evidence"],"source_hash":"9c7e190f408acac5ae5441ca34c4e3f3797a1eed7f93cb7d9bb65a321ee00c44","slug":"health-experiences-comment-5670","classification":{"id":"HHS-OASH-2026-0397-5670","body_sha256":"ed599fd810c8ecb1d8ba1e5d81f8dea9607b669295c2eefd7376ef5c46705d97","status":"ai_reviewed","primary_topic":"mechanisms","topics":[{"id":"mechanisms","evidence":"Wireless radiation disrupts lymphocytes by opening calcium channels (VGCC's) in cell membrane"},{"id":"research","evidence":"Studies that shows that wireless radiation affects vitamin D and glutathione:"},{"id":"occupational","evidence":"radar workers, after 10 years, had glutathione that was more than 50% lower than non-radar workers."},{"id":"ehs","evidence":"found reduced levels of glutathione and impaired detoxification ability in those with microwave sickness (EHS)."}],"summary":"Summarizes cited research concerning immune function, DNA repair, calcium channels, vitamin D and antioxidant responses to wireless exposure. Also discusses occupational radar studies and proposed genetic and biochemical contributors to EHS.","reviewed_at":"2026-10-27T23:26:06Z","review_method":"Full comment-text review with exact source evidence; attachments not reviewed","review_source_sha256":"33324b8db647937ab5bf3049e6656b1572c8f8cf25a585ccd83c2ddcc58a04da","source_url":"https://rfsafe.net/hhs-comments/data/catalog.json","scope":"Original comment body; attachments excluded"},"forum_topics":["mechanisms","research","occupational","ehs"],"primary_topic":"mechanisms","forum_title":"Summarizes cited research concerning immune function, DNA repair, calcium channels, vitamin D and antioxi…"}