{"id":"HHS-OASH-2026-0397-6364","number":"6364","name":"Alex Andreasen","organization":"","posted":"2026-10-28T04:00Z","received":"2026-10-21T04:00Z","body":"https://www.tandfonline.com/doi/abs/10.1080/15513815.2019.1692112\n\n\"Does Exposure of Smart Phones during Pregnancy Affect the Offspring’s Ovarian Reserve? A Rat Model Study\"\n\n\"Abstract\nWe investigated the effect of prenatal exposure to smart phone radiation and the protective effect of omega-3 on ovarian reserve of offspring. Methods: 24 pregnant Wistar albino rats were divided into four groups. Group-I received neither radiofrequency (RF) radiation nor omega-3, group-II received RF, group-III received RF radiation and 300 mg omega-3 and group-IV received RF radiation and 600 mg Omega-3 till birth. At 42 days, bilateral oophorectomy was performed on all female offspring for follicle count and immunohistochemical staining (GDF9, FOXO1 and TUNEL). Results: Group-II had significantly lower mean number of primordial (p = 0.006), secondary follicles(p = 0.003) and a higher atresia score. Group-III variables were comparable with group-I variables. Group-IV had statistically higher median number of atretic follicles than group-I (p = 0.023). Conclusions: Ovarian reserve of offspring diminished with RF exposure during pregnancy. Omega-3 supplementation during pregnancy may reduce the potential premature ovarian failure.\"","attachments":[],"attachment_inventory":true,"withheld":false,"source":"https://www.regulations.gov/comment/HHS-OASH-2026-0397-6364","tags":["child-development","research-evidence"],"source_hash":"8f0e67a3e1699ecf3e694eb43ba9a712d245889c8b40d2d912655553e218d88f","slug":"child-development-comment-6364","classification":{"id":"HHS-OASH-2026-0397-6364","body_sha256":"87900190ba82e9da3b0c8c02d046d6725771772e5079c24a191ade408570a222","status":"ai_reviewed","primary_topic":"research","topics":[{"id":"research","evidence":"cy Affect the Offspring’s Ovarian Reserve? A Rat Model Study\"\n\n\"Abstract\nWe investigated the effect of prenatal exposure to s"},{"id":"reproductive","evidence":"tion and the protective effect of omega-3 on ovarian reserve of offspring. Methods: 24 pregnant Wistar albino rats were divid"}],"summary":"The commenter quotes a rat study of prenatal mobile-phone exposure, ovarian reserve and omega-3 supplementation.","reviewed_at":"2026-10-28T23:54:32Z","review_method":"Full comment-text review with exact source evidence; attachments not reviewed","review_source_sha256":"c0cce43d5f3a7c1988482d7bb2940b7a8fd343aa351575bf7e1572c559a11bdc","source_url":"https://rfsafe.net/hhs-comments/data/catalog.json","scope":"Original comment body; attachments excluded"},"forum_topics":["research","reproductive"],"primary_topic":"research","forum_title":"The commenter quotes a rat study of prenatal mobile-phone exposure, ovarian reserve and omega-3 supplemen…"}